Results 161 to 170 of about 1,018,348 (314)

Engineering a Virus‐Derived X Family DNA Polymerase FvPolX for de novo DNA Synthesis

open access: yesAdvanced Science, EarlyView.
In this study, a Faustovirus‐derived polymerase (FvPolX) is engineered based on structural and sequence analysis of PolX enzymes. The optimal mutants demonstrate substantially enhanced catalytic activity toward dNTPs and 3′‐ONH2‐dNTPs compared to the wild‐type enzyme.
Chengjie Zhang, Lei Du, Shengying Li
wiley   +1 more source

Synergistic Organic–Inorganic Interface Engineering for Stable Zinc Metal Anodes in Aqueous Batteries

open access: yesAdvanced Science, EarlyView.
A multifunctional mercaptosuccinic acid enables an ultrathin organic–inorganic SEI (Zn‐S‐RCOOH) that synergistically regulates interfacial water and accelerates Zn2+ transport. The optimized hydrogen‐bond environment and ZnS‐guided deposition suppress dendrites, corrosion, and by‐product formation, delivering ultrastable Zn cycling and high‐performance
Huaichong Sun   +11 more
wiley   +1 more source

Degradation Mechanisms Associated with Electron‐Blocking Layers in Inverted Perovskite Solar Cells

open access: yesAdvanced Science, EarlyView.
The effects of the three typical EBLs NiOx, PTAA, and 2PACz on the photovoltaic performance and degradation mechanisms are investigated under light soaking and solar‐thermal cycling conditions of corresponding PSCs, demonstrating that 2PACz is the best EBL due to the better interface contact and lower lattice distortion.
Xiongzhuo Jiang   +9 more
wiley   +1 more source

A Crack‐Based One‐Dimensional Microspheres Array Enables Thermal–Mechanical Decoupled Dual‐Functional Sensing

open access: yesAdvanced Science, EarlyView.
Inspired by Nostoc, a crack‐based one‐dimensional microspheres array (COMA) sensor is developed, which stabilizes crack geometry under isotropic expansion, enabling a predictable, monotonic thermal response from which true strain can be accurately extracted. The COMA sensor exhibits high sensitivity at ultralow deformation (gauge factor up to 89) and a
Wanqing Xu   +7 more
wiley   +1 more source

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

open access: yesAdvanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu   +15 more
wiley   +1 more source

Copyright versus Patents: the Open Source Software Legal Battle [PDF]

open access: yes
Open Source Software is often viewed as an anti-intellectual property regime. By contrast, we argue how IP law is at the heart of open source model since licenses that organize the innovation and business relationships between developers, distributors ...
François Lévêque, Yann Ménière
core  

Physics‐Constrained Constitutive Learning of Rate‐Limiting Timescales for Efficient Hydrogen‐Based Direct Reduction for Green Steel Making

open access: yesAdvanced Science, EarlyView.
A conversion‐resolved constitutive framework is developed for the hydrogen‐based direct reduction of iron oxide pellets. Effective reaction and transport timescales are inferred directly from measured trajectories and mapped against operating conditions, pellet architecture, and composition. The analysis reveals how late‐stage transport control emerges
Anurag Bajpai   +3 more
wiley   +1 more source

Developing Micro/Nanostructured Fluidic Mixing Technology for Biomedical Applications

open access: yesAdvanced Science, EarlyView.
This review critically evaluates how micro/nanostructured mixing technologies are redefining biomedical research. By synergizing fundamental analysis, numerical modeling, structural design, and external field manipulation, these systems attain unprecedented control over mass transport.
Junkai Wang   +3 more
wiley   +1 more source

Deciphering the Dynamic Balance Between Solvation Strength and Polysulfides Reaction Heterogeneity in Practical Lithium‐Sulfur Batteries

open access: yesAdvanced Science, EarlyView.
A weakly solvating fluorinated cosolvent (1200ET) enables precise solvation‐power regulation in Li–S batteries, decoupling interfacial stabilization from sulfur redox kinetics. This approach suppresses polysulfide dissolution while preserving reaction kinetics, leading to a stable Li metal interface and high‐energy multilayer pouch cells, revealing a ...
Huidong Dai   +9 more
wiley   +1 more source

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