Results 61 to 70 of about 14,516,347 (349)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Mapping the intellectual structure of scientific outputs in the subject area of public law in the Web of Science database [PDF]

مجله علم‌سنجی کاسپین
Background and aim: Given the fundamental role of public law in regulating the relationship between the state and citizens and safeguarding fundamental rights, examining the intellectual structure and scientific trends in this field is essential for the ...
Omid Shirzad, Ismael Mostafavi, Seyedeh Zahra Hosseini Rad   +2 more
doaj  

PENGARUH STRUKTUR KEPEMILIKAN, UKURAN PERUSAHAAN, DAN UMUR PERUSAHAAN TERHADAP KINERJA INTELLECTUAL CAPITAL (Studi pada Perusahaan Perbankan yang Terdaftar di Bursa Efek Indonesia Tahun 2007-2009) [PDF]

, 2011
The purpose of this research was to investigate the influence of ownership structure, firm size, and firm age on the firm performance with intellectual capital performance as dependen variable.
MEIRANTO, Wahyu, PUTRI, Gelisha Dian Kharisma   +1 more
core  

Genomic structural variants are linked with intellectual disability [PDF]

Journal of Neural Transmission, 2015
Mutations in more than 500 genes have been associated with intellectual disability (ID) and related disorders of cognitive function, such as autism and schizophrenia. Here we aimed to unravel the molecular epidemiology of non-specific ID in a genetic isolate using a combination of population and molecular genetic approaches.
Bulayeva, Kazima, Lesch, Klaus-Peter, Bulayev, Oleg, Walsh, Christopher, Glatt, Stephen, Gurgenova, Farida, Omarova, Jamilja, Berdichevets, Irina, Thompson, Paul M   +8 more
openaire   +3 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Evolution of the Socio-cognitive Structure of Knowledge Management (1986–2015): An Author Co-citation Analysis

Journal of Data and Information Science, 2019
The evolution of the socio-cognitive structure of the field of knowledge management (KM) during the period 1986–2015 is described.
González-Valiente Carlos Luis, Santos Magda León, Arencibia-Jorge Ricardo   +2 more
doaj   +1 more source

The Nuclear Physics of Neutron Stars

, 2013
We explore the unique and fascinating structure of neutron stars. Although neutron stars are of interest in many areas of Physics, our aim is to provide an intellectual bridge between Nuclear Physics and Astrophysics.
Piekarewicz, J.
core   +1 more source

Supply chain management as the key to a firm’s strategy in the global marketplace [PDF]

, 2015
Purpose: This research aims to analyze the intersection of two literature streams: that of strategy and supply chain management (SCM). This review should create a better understanding of “strategic SCM” by focusing on relevant theories in the strategic ...
Dr Xenophon Koufteros, Marina Dabic, Miguel Gonzalez-Loureiro, Professor Maria Jesus Saenz, Timothy Kiessling   +4 more
core   +1 more source

Multiple-valued structures of intellectual systems [PDF]

2016 XIth International Scientific and Technical Conference Computer Sciences and Information Technologies (CSIT), 2016
The conversion units and data transfer with frequency data coding are perspective for a reliability raising and transmission accuracy of the information in control systems, communication systems, computer networks etc. One of directions in creation of high-reliable microelectronic components of computer facilities and control systems is the development
Grygoryy Chetverikov, Oleksiy Puzik, Iryna Vechirska   +2 more
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source