Results 81 to 90 of about 3,408 (305)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Why Intellectualism Still Fails [PDF]

open access: yes, 2016
Intellectualism about knowledge-how is the view that knowing how to do something amounts to knowing a fact. The version of intellectualism defended by Jason Stanley and Timothy Williamson holds that knowledge-how is a species of knowledge-wh, i.e ...
Ditter, Andreas
core  

Anti-Intellectualism, Incentive, and Susceptibility to Misinformation

open access: yes, 2021
This study tests whether anti-intellectualism predicts susceptibility to misinformation, and whether being incentivized to be accurate moderates that susceptibility. Past research links lack of mental effort to misinformation susceptibility.
Scott Eidelman, Marie Altgilbers Roweton
core   +1 more source

Intellectual Pride And Intellectual Humility [PDF]

open access: yes, 2017
Pride is a notion with both positive and negative connotations. On the one hand, we urge people to take pride in their work, and we think it appropriate to be proud of the achievements of our offspring. And yet, on the other hand, pride can also be negative – it is what comes before a fall, after all; after hubris comes nemesis.
Kallestrup, Jesper, Pritchard, Duncan
openaire  

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

A Scale for Measuring Students' Anti-Intellectualism

open access: yes, 2001
Two studies were conducted which report the development and testing of the Student Anti-Intellectualism Scale, designed as a measure of anti-intellectual attitudes in students enrolled in higher education.
Martin E. Eigenberger   +1 more
core   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

Anti-intellectualism and Conspiracy Theory

open access: yes, 2022
This paper tries to demonstrate the relationship of anti- intellectualism with conspiracy theory. For this, firstly, the paper provides a critical reading of the story of Polyphemus in Homers Odyssey to show that anti-intellectualism is rooted on the one-
안재원
core  

Biased Assimilation, Attitude Polarization, and Anti-Intellectualism

open access: yes, 2023
This study will test whether biased assimilation and attitude polarization increase as anti-intellectualism ...
Scott Eidelman, Marie Altgilbers Roweton
core   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +9 more
wiley   +1 more source

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