Results 41 to 50 of about 1,386,089 (263)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

National Intelligence Daily 20 December 1983 [PDF]

open access: yes, 1983
Declassified on 2017-11 ...
United States. Central Intelligence Agency.   +1 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

TRAGOM PISANE RIJEČI VJERSKE INTELIGENCIJE BOŠNJAKA U AUSTROUGARSKOM RAZDOBLJU I NJIHOVA PROSVJETITELJSKA ULOGA // WRITTEN WORDS OF BOSNIAK RELIGIOUS INTELIGENTSIA IN AUSTRO-HUNGARIAN PERIOD AND ITS ENLIGHTENING ROLE [PDF]

open access: yesHistorijski pogledi, 2019
The paper provides a brief overview of the significance and role of religious intelligence of Bosniaks in the field of affirmation of written texts in the Austro-Hungarian period.
Edin Veladžić
doaj  

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Social intelligence design in ambient intelligence [PDF]

open access: yesAI & SOCIETY, 2009
This Special Issue of AI and Society contains a selection of papers presented at the 6th Social Intelligence Design Workshop held at ITC-irst, Povo (Trento, Italy) in July 2007. Being the 6th in a series means that there now is a well-established and also a growing research area. The interest in this research area is growing because, among other things,
Anton Nijholt   +2 more
openaire   +1 more source

National Intelligence Daily (Cable) 24 March 1982 [PDF]

open access: yes, 1982
Declassified on 2017-11 ...
United States. Central Intelligence Agency.   +1 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The role of competitive intelligence in ensuring the economic security of enterprises [PDF]

open access: yesKošická bezpečnostná revue, 2018
The article is devoted to the issues of commercial intelligence and, related to this, the security of the enterprise. The article describes the nature, tasks, approaches to the definition of principles and the selection of effective methods of organizing
Volodymyr SIDAK   +2 more
doaj  

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