Results 31 to 40 of about 646,422 (296)

Enhanced Immune Responses by Virus-Mimetic Polymeric Nanostructures Against Infectious Diseases

Frontiers in Immunology, 2022
Intermittent outbreaks of global pandemic disease have spurred new sensors and medicines development for the prevention of disease spread. This perspective specifically covers recent advances, challenges, and future directions in virus-mimetic polymeric ...
Xinpei Li, Xinpei Li, Shengqiu Liu, Shengqiu Liu, Panchao Yin, Panchao Yin, Kun Chen, Kun Chen   +7 more
doaj   +1 more source

From Cosmos to Intelligent Life: The Four Ages of Astrobiology

, 2012
The history of life on Earth and in other potential life-bearing planetary platforms is deeply linked to the history of the universe. Since life as we know it relies on chemical elements forged in dying heavy stars, the universe needs to be old enough ...
Abel, Arrhenius, Bonner, Fenchel, Fitz, Gleiser, Kaltenegger, Lunine, Marcelo Gleiser, Oparin, Prigogine, Salama, Smoot, Susskind, Susskind, Ward, Webb, Weinberg   +17 more
core   +1 more source

Quintessence Cosmology and the Cosmic Coincidence [PDF]

, 2001
Within present constraints on the observed smooth energy and its equation of state parameter, it is important to find out whether the smooth energy is static (cosmological constant) or dynamic (quintessence).
A. Balbi, A.G. Riess, A.R. Cooray, A.R. Cooray, B. Ratra, C. Armendariz-Picon, C. Wetterich, G. Efstathiou, G.P. Holder, I. Maor, J. Garriga, J.A. Newman, L.A. Ureña-López, M. Roos, M. Tegmark, N. Bahcall, P. Garnavich, P.J. Steinhardt, P.J.E. Peebles, R. Bean, S. A. Bludman, S. Bludman, S. Perlmutter, S. Weinberg, S. Weinberg, S.M. Harun-or-Rashid, T. Matos, V. Barger, W.L. Freedman, Z. Haiman   +29 more
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

All-in-one wearable drug efficacy assessment systems for bulbar muscle function using amyotrophic lateral sclerosis animal models

Nature Communications
Preclinical studies are crucial for developing amyotrophic lateral sclerosis drugs. Current FDA-approved drugs have been created by monitoring limb muscle function and histological analysis of amyotrophic lateral sclerosis model animals.
Beomjune Shin, Youngjin Kwon, Michelle Mittaz, Hojoong Kim, Xiaoxing Xu, Eugene Kim, Yoon Jae Lee, Jimin Lee, Woon-Hong Yeo, Hyojung J. Choo   +9 more
doaj   +1 more source

Heparin-loaded hierarchical fiber/microsphere scaffolds for anti-inflammatory and promoting wound healing

Smart Materials in Medicine
Chronic non-healing wounds induced by oxidative stress and inflammation can activate inflammatory cells and produce large amounts of inflammatory mediators, which fail to maintain homeostasis in the skin and delay the wound-healing process.
Kai Cheng, Yan Deng, Lin Qiu, Shuhang Song, Lei Chen, LinGe Wang, Qianqian Yu   +6 more
doaj   +1 more source

Tunable two-dimensional superconductivity and spin-orbit coupling at the EuO/KTaO3(110) interface

npj Quantum Materials, 2022
Unconventional quantum states, most notably the two-dimensional (2D) superconductivity, have been realized at the interfaces of oxide heterostructures where they can be effectively tuned by the gate voltage (V G).
Xiangyu Hua, Fanbao Meng, Zongyao Huang, Zhaohang Li, Shuai Wang, Binghui Ge, Ziji Xiang, Xianhui Chen   +7 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Stimuli-responsive antimicrobial polymer systems: From structural design to biomedical applications

Giant
Bacterial infections and drug-resistant evolution have seriously threatened public health. Stimuli-responsive antimicrobial materials have been rapidly developed to address the evolving challenges posed by multi-drug-resistant bacteria.
Jia Guo, Yaqi Tao, Zhen Du, Siqi Zhang, Wei Zheng, Zhibo Wang, Zhuomin Yi, Yangqing Gou, Wen Tang   +8 more
doaj   +1 more source

Deep learning enabled topological design of exceptional points for multi-optical-parameter control

Communications Physics, 2023
Metasurfaces are 2D artificial nanostructures that exhibit fascinating optical phenomena and flexible capabilities. Multi-optical-parameter metasurfaces have advantages over single-function or single-dimensional metasurfaces, especially in practical ...
Peng Fu, Shuo Du, Wenze Lan, Leyong Hu, Yiqing Wu, Zhenfei Li, Xin Huang, Yang Guo, Weiren Zhu, Junjie Li, Baoli Liu, Changzhi Gu   +11 more
doaj   +1 more source