Results 21 to 30 of about 20,017 (219)

Dynamic deformation and disaster mechanical mechanism of coal under dynamic true triaxial synchronous impact loading

open access: yesMeitan xuebao
During the reuse of underground space in mine, coal masses are subjected to multi-axial and multi-directional dynamic disturbances induced by multiple sources, such as instantaneous strata fracturing, blasting, and earthquakes, thereby increasing the ...
Shiwei ZHANG   +7 more
doaj   +1 more source

Performance evaluation and selection of the core drill bits for lunar rock

open access: yesGeomechanics and Geophysics for Geo-Energy and Geo-Resources
The objective of this study is to systematically examine the drilling efficiency and performance of various core drill bits in lunar rock formation using the discrete element method (DEM) and drilling experiments conducted in a lunar vacuum environment ...
Xuan Wang   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Energy Release Mechanism of Underwater Implosion With Different Structural Bodies

open access: yesGeofluids
Underwater implosion is typically accompanied by intense shock wave energy. The investigation of its energy release mechanism is crucial for structural safety protection, marine environmental monitoring, ocean acoustic field analysis, and energy ...
Yuhao Zhang   +5 more
doaj   +1 more source

Design and experimental study of a tethered self-excavating drilling and coring scheme for lunar deep mining

open access: yesMeitan kexue jishu
The development and utilization of lunar mineral resources is an important way to solve the earth’s energy crisis. Drilling and coring, an effective method for lunar section sample collection, is a key prerequisite for accurately identifying the ...
Mingzhong GAO   +10 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Research on train wheel point cloud registration algorithm based on key points by fusing Super-4PCS and ICP

open access: yesScientific Reports
Wheels are critical components of railway vehicles, and the dynamic measurement of wheel parameters is of paramount importance for the safe operation of trains.To enhance the matching accuracy in the existing dynamic measurement processes for train wheel
Qian Xiao   +5 more
doaj   +1 more source

Interpretable Data-Driven Explicit Shear Formula for Keyed Dry Joints Considering Steel Fiber Contribution

open access: yesBuildings
Precast concrete segmental bridges rely on keyed dry joints to transfer shear forces, yet existing formulas have insufficient accuracy for normal concrete (NC) and ultra-high-performance concrete (UHPC) joints.
Qingkun Wei   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Fatigue damage assessment of bogie frame based on an improved nonlinear cumulative damage model

open access: yesScientific Reports
The structural damage of rail vehicle bogie frames is mostly caused by fatigue cumulative damage under the action of multi-level complex loads. Under complex loads, the sequence effect and coupling effect between loads have a significant impact on ...
Qian Xiao   +3 more
doaj   +1 more source

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