Results 41 to 50 of about 1,372 (291)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Semantic Segmentation and Effect Optimization of 3D Point Cloud Based on 2D Semantic Segmentation and Clustering for Construction Machinery Unstructured Environment

open access: yesSensors
The operational environment of construction machinery is predominantly unstructured, characterized by rapid changes, high complexity, and irregularly distributed objects.
Shengjie Fu   +6 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Marx’s Thoughts on Human Essence and Its Realistic Significance from the Perspective of Artificial Intelligence

open access: yesComputer Sciences & Mathematics Forum, 2023
The evolution of Marx’s ideation was accompanied by a continuous, in-depth understanding of human essence. From the promotion of human self-consciousness to the status of divinity to the transformation of humans into a human essence, his thoughts turned ...
Youqiang Wang, Xuan Kang, Jiayue Xiong
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Key technology for unattended intelligent operation of tubular heater in long-distance oil and gas pipelines

open access: yesYou-qi chuyun, 2022
As the key equipment of long-distance oil and gas pipeline stations, the tubular heater system of the long-distance pipeline in China has realized the automatic control based on the solidification procedure of PLC by now.
JIA Chunhua   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Applying Job-Know Ontology towards Linking Workforce Experience and Labor Productivity in Smart Factory Industry 4.0

open access: yes, 2019
Industrialization of Artificial Intelligence (AI) raises several questions, inter alia, whether machines can gain work experience alike human workforce, whether the on-the-job obtained experiences may enrich existing knowledge, skills and abilities ...
Ansari, Fazel   +2 more
core   +4 more sources

Mechanized Transformation in Shellfish Aquaculture: Practical Challenges and Intelligentization-Driven Breakthrough Pathways [PDF]

open access: yes
Under the dual pressure of global aquatic resource constraints and the transformation to a low-carbon economy, intelligent technologies are reshaping the underlying logic of the shellfish farming industry.
Zhu Shenghu, Ji Yongjin, Wang Yuting
core   +1 more source

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