Results 41 to 50 of about 1,372 (291)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
The operational environment of construction machinery is predominantly unstructured, characterized by rapid changes, high complexity, and irregularly distributed objects.
Shengjie Fu +6 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The evolution of Marx’s ideation was accompanied by a continuous, in-depth understanding of human essence. From the promotion of human self-consciousness to the status of divinity to the transformation of humans into a human essence, his thoughts turned ...
Youqiang Wang, Xuan Kang, Jiayue Xiong
doaj +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
As the key equipment of long-distance oil and gas pipeline stations, the tubular heater system of the long-distance pipeline in China has realized the automatic control based on the solidification procedure of PLC by now.
JIA Chunhua +3 more
doaj +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Industrialization of Artificial Intelligence (AI) raises several questions, inter alia, whether machines can gain work experience alike human workforce, whether the on-the-job obtained experiences may enrich existing knowledge, skills and abilities ...
Ansari, Fazel +2 more
core +4 more sources
Mechanized Transformation in Shellfish Aquaculture: Practical Challenges and Intelligentization-Driven Breakthrough Pathways [PDF]
Under the dual pressure of global aquatic resource constraints and the transformation to a low-carbon economy, intelligent technologies are reshaping the underlying logic of the shellfish farming industry.
Zhu Shenghu, Ji Yongjin, Wang Yuting
core +1 more source

