Results 71 to 80 of about 131,298 (249)

Enhancing Nucleation using a Vortex-based Hydrodynamic Cavitation Device: Application to Antisolvent Crystallization of Paracetamol – Methanol – Water System

Ultrasonics Sonochemistry
Nucleation is the onset of the crystallization process, and enhancing its rate is fundamental to intensifying crystallization, be it in a batch or continuous mode of operation.
Vidit Tiwari, Subhrajit Swain, Vivek V. Ranade   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Numerical Investigation of the Influence of Temperature on Fluidization Behavior: Importance of Particle Collision Parameters and Inter-Particle Forces

Fluids
Fluidized bed reactors (FBRs) are integral to various industries due to their exceptional capability in facilitating efficient gas–solid interactions, resulting in superior mixing and heat and mass transfer.
Milan Mihajlović, Juan G. Ramírez, Ildefonso Campos Velarde, Martin Van Sint Annaland, Ivo Roghair   +4 more
doaj   +1 more source

Recent Increase of Tropical Cyclone Rapid Intensification in Global Coastal Regions [PDF]

, 2022
Yi Li, Youmin Tang, Shuai Wang, Ralf Toumi   +3 more
openalex   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Effect of Oxidants in the Utilization of Polysulfone Hollow Fiber Membrane Module as Bubble Reactor for Simultaneously Removal of NOx and SO2

International Journal of Technology
Air pollution has become a global issue and contributes significantly to climate change, mainly due to the massive energy consumption in industry and the transportation sector.
Sutrasno Kartohardjono, Eva Fathul Karamah, Adinda Puspa Hayati, Grace Natalie Talenta, Thoriq Ahmad Ghazali, Woei Jye Lau   +5 more
doaj   +1 more source

Agriculturally intensified landscapes are associated with reduced body condition of lady beetles [PDF]

, 2022
Julia Tiede, Benjamin Iuliano, Claudio Gratton   +2 more
openalex   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source