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Gradients and intensity modulated radiotherapy
Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Cat. No.00CH37143), 2002A consequence of the advent of intensity modulated radiation therapy (IMRT) is the presence of large dose gradients surrounding the tumor, and the regions at risk (RAR's) near the tumor. Unlike standard radiotherapy, these gradients are not the chance result of a few beam choices, but rather they are strategically placed by the optimization software. A
J.M. Kapatoes +5 more
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Optimizing the planning of intensity-modulated radiotherapy
Physics in Medicine and Biology, 1994A method of computing optimized intensity-modulated beam profiles has been further developed and used to generate highly conformal radiotherapy dose distributions. The features of these distributions are shown to be strongly dependent on the tuning built into the algorithm.
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Quality assurance of intensity-modulated radiotherapy
Seminars in Radiation Oncology, 2002Intensity-modulated radiation therapy (IMRT) requires the use of inverse treatment planning and nonuniform fluence beams delivered by a series of complex radiation portals. The quality assurance procedures for conventional three-dimensional conformal radiation therapy (3D-CRT) have been developed and are in worldwide clinical use, but the more complex ...
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Salvage radiotherapy: A plea for dose-escalation with intensity-modulated radiotherapy
European Journal of Cancer, 2012We would like to congratulate Ohri et al. with their recent systematic review, addressing both the timing and dose of salvage radiotherapy (SRT) for prostate cancer. Their model confirms previous reports that the therapeutic ratio of SRT might be improved by initiating treatment at low prostate specific antigen (PSA) levels.
Piet, Ost +3 more
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Rectal Radiotherapy — Intensity-modulated Radiotherapy Delivery, Delineation and Doses
Clinical Oncology, 2016The use of intensity-modulated radiotherapy in rectal cancer is attractive in that it may reduce acute and late toxicities and potentially facilitate dose escalation. Intensity-modulated radiotherapy probably has a role in selected patients, but further investigation is required to identify the parameters for selection.
S, Teoh, R, Muirhead
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Intensity-modulated Radiotherapy in the Treatment of Breast Cancer
Clinical Oncology, 2012Intensity-modulated radiotherapy (IMRT) is a newer method of radiotherapy that uses beams with multiple intensity levels for any single beam, allowing concave dose distributions and tighter margins than those possible using conventional radiotherapy. IMRT is ideal for treating complex treatment volumes and avoiding close proximity organs at risk that ...
I, Dayes +4 more
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Intensity-modulated Radiotherapy in the Treatment of Lung Cancer
Clinical Oncology, 2012Intensity-modulated radiotherapy (IMRT) is an advancement in radiotherapy that uses intensity-modulated beams, which can provide multiple intensity levels for any single beam direction and any single source position, allowing shaped distributions and dose gradients with narrower margins than previously possible.
A, Bezjak +4 more
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Intensity-modulated radiotherapy for lymphoma involving the mediastinum
International Journal of Radiation Oncology*Biology*Physics, 2005To determine the feasibility, potential advantage, and indications for intensity-modulated radiotherapy (IMRT) in the treatment of Hodgkin's lymphoma or non-Hodgkin's lymphoma involving excessively large mediastinal disease volumes or requiring repeat RT.Sixteen patients with Hodgkin's lymphoma (n = 11) or non-Hodgkin's lymphoma (n = 5) undergoing ...
Karyn A, Goodman +4 more
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Intensity-modulated radiotherapy for carcinoma of the head and neck
Current Oncology Reports, 2003Intensity-modulated radiotherapy (IMRT) is the next evolutionary step of three-dimensional conformal radiotherapy (3-DCRT). IMRT plans are generated with computer-optimized nonuniform radiation beam intensities incident on a target or patient. The dose distributions in IMRT show significantly higher conformality compared with other methods of external ...
José A, Peñagarícano +1 more
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Intensity-modulated Radiotherapy in the Treatment of Prostate Cancer
Clinical Oncology, 2012Three-dimensional conformal radiotherapy (3DCRT) as the primary treatment for prostate cancer has improved outcomes compared with conventional radiotherapy, but with an associated increase in toxicity due to radiation effects on the bladder and rectum.
G, Bauman +4 more
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