Results 111 to 120 of about 11,212,414 (344)

Lp-intensities of random measures

Stochastic Processes and their Applications, 1979
Abstract Given a random measure η and a fixed number p>1, the Lp-intensity ‖η‖p of ηis defined as the total variation measure of the subadditive set function ‖η(·)‖p. It is shown that ‖η‖p can exist (be locally finite) only if the usual intensity measure Eη exists and η 《 E η a.s, and that in this case ‖η‖ p B =ʃ B ‖ d η ...
openaire   +2 more sources

Measurement of structural intensity [PDF]

The Journal of the Acoustical Society of America, 1995
The modeling of structural behavior leads to simplified models of very often complex structures. To get a better understanding of the energy flow inside and out of the structures, the development of measurement methods is very important. Dynamic movements are associated with vibratory and acoustic energy dissipation.
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

A Proposal of a Synthetic Indicator to Measure Poverty Intensity, With an Application to EU-15 Countries [PDF]

This paper deals with the proposal of a synthetic indicator to measure intensity of poverty. So, whereas incidence of poverty can be clearly measured using the headcount ratio indicator, according to Sen (1976) dimensions of poverty, the choice of a ...
José Javier Núñez-Velázquez, Juana Domínguez-Domínguez   +1 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Viewing distance matters to perceived intensity of facial expressions.

Frontiers in Psychology, 2015
In our daily perception of facial expressions, we depend on an ability to generalize across the varied distances at which they may appear. This is important to how we interpret the quality and the intensity of the expression.
Andreas eGerhardsson, Lennart Björn Högman, Håkan eFischer   +2 more
doaj   +1 more source

Reduced coherence in double-slit diffraction of neutrons

, 2007
In diffraction experiments with particle beams, several effects lead to a fringe visibility reduction of the interference pattern. We theoretically describe the intensity one can measure in a double-slit setup and compare the results with the ...
A. Viale, B. Vacchini, E. Joos, N. Zanghì, P. Facchi, R. Tumulka   +5 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source