Results 121 to 130 of about 11,212,414 (344)

Development of a scale to measure perceived intensity of sponsorship activities

open access: yesTržište, 2006
The purpose of research was the development of a scale to be used in measuring perceived intensity of sponsorship activities. Psychometric adequacy of the initial set of items is analyzed by assessing reliability, convergent validity and dimensionality ...
Edo Rajh, Ljiljana Božić
doaj  

Blue-light induced infrared absorption in KNbO3 [PDF]

open access: yes, 1994
We have used a high-finesse cavity to measure the cw intensity dependence and dynamics of blue-light-induced infrared absorption (BLIIRA) in KNbO3 crystals for blue-light intensities between 7 x 10^-4 and 2 x 10^4 W/cm^2.
Kimble, H. J.   +2 more
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

A Note on the Intensity of Downside Risk Aversion [PDF]

open access: yes
In this note we show that the measure of intensity of downside risk aversion proposed recently by Crainich and Eeckhoudt (2007) cannot be guaranteed to exist. We do this by means of an example in which the existence of the measure depends upon the values
Francisco J. Vazquez, Richard Watt
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Recruiting Intensity during and after the Great Recession: National and Industry Evidence [PDF]

open access: yes
We measure job-filling rates and recruiting intensity per vacancy at the national and industry levels from January 2001 to September 2011 using data from the Job Openings and Labor Turnover Survey.
John C. Haltiwanger   +2 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Posterior analysis for some classes of nonparametric models [PDF]

open access: yes
Recently, James [15, 16] has derived important results for various models in Bayesian nonparametric inference. In particular, he dened a spatial version of neutral to the right processes and derived their posterior distribution. Moreover, he obtained the
Antonio Lijoi   +2 more
core  

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