Results 241 to 250 of about 1,032,894 (314)

Meibum Lipid Saturation Related to Dry Eye, Age, and Sex Using Nuclear Magnetic Resonance Spectroscopy. [PDF]

Invest Ophthalmol Vis Sci
Machane D, Shaji MS, Borchman D, Jaeger V.   +3 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Postauricular Muscle Reflex as a Potential Objective Measure of Auditory Function in Normal-Hearing Adults. [PDF]

Sensors (Basel)
Müller JE, Vargas Luna JL, Korth D, Richter D, Volk GF, Baljić I, Guntinas-Lichius O.   +6 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Affective Reactivity to a Single Bout of High-Intensity Interval Training in Schizophrenia: A Randomized Controlled Trial. [PDF]

Schizophr Bull Open
Sanden M, Pauck Bernhardsen G, Hanssen-Bauer K, Høye A, Johnsen E, Morken G, Nygård M, Abel Engh J.   +7 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Duration of agricultural pesticide exposure application and Parkinson's disease in California's central valley. [PDF]

Environ Res Health
Gong Y, Paul KC, Del Rosario IPC, Zhang K, Cockburn MG, Thompson LK, Keener AM, Bronstein JM, Ritz BR.   +8 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Towards Intelligent Pain Monitoring Systems: A Survey of Recent Technologies and Methods. [PDF]

Sensors (Basel)
Naseer A, Tayyib N, Rashid S.
europepmc   +1 more source

An Agent-Based Model for Simulating Flood Governance and Community Resilience. [PDF]

MethodsX
Zhu A, Feng W, Zheng H, Huang Y, He X, Zhou C, Yang LE.   +6 more
europepmc   +1 more source