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Intensity modulated radiotherapy

2012
Intensity-modulated radiotherapy (IMRT) is a radiation delivery technique that allows “dose sculpting” to improve target coverage while sparing normal tissues. In an IMRT plan, the number of photons delivered (or “fluence”) varies within a field. Such variability can be used to avoid normal structures with lower radiation tolerance than the cancer and ...
Bridget F. Koontz   +2 more
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Conformal Radiotherapy and Intensity-modulated Radiotherapy: Clinical Data

Acta Oncologica, 2000
Conformal radiotherapy (CRT) is based on three hypotheses: (i) a higher rate of local control can improve the survival rate; (ii) dose escalation can increase tumor control; and (iii) CRT allows the delivery of higher doses by decreasing the incidence of late effects. These postulates are now supported by several data.
M, Tubiana, F, Eschwège
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Submandibular Gland-sparing Intensity-modulated Radiotherapy

American Journal of Clinical Oncology, 2014
Xerostomia is one of the most debilitating late effects of head and neck radiotherapy (RT) and significantly impacts quality of life. The submandibular gland (SMG) provides approximately 70% of the unstimulated saliva that accounts for about 95% of the salivary flow during a 24-hour period. Intensity-modulated RT (IMRT) has been used in recent years to
William M, Mendenhall   +2 more
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Intensity-Modulated Radiotherapy for Pancreatic Adenocarcinoma

International Journal of Radiation Oncology*Biology*Physics, 2012
To report the outcomes and toxicities in patients treated with intensity-modulated radiotherapy (IMRT) for pancreatic adenocarcinoma.Forty-seven patients with pancreatic adenocarcinoma were treated with IMRT between 2003 and 2008. Of these 47 patients, 29 were treated adjuvantly and 18 definitively.
Jonathan A, Abelson   +11 more
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Practical experience with intensity-modulated radiotherapy

The British Journal of Radiology, 2004
At the Ipswich Hospital implementation of intensity-modulated radiotherapy (IMRT) commenced in February 2001 based on an established 3D conformal radiotherapy (3D CRT) service. This paper describes our experiences as we commissioned a fully-integrated IMRT planning and delivery system, and established IMRT within the department.
H V, James, C D, Scrase, A J, Poynter
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Intensity-modulated radiotherapy for sinonasal teratocarcinosarcoma

Journal of Huazhong University of Science and Technology [Medical Sciences], 2011
Surgical excision and postoperative radiotherapy are widely accepted therapeutic modalities for sinonasal teratocarcinosarcoma (SNTCS). Previous studies have shown that intensity-modulated radiation therapy (IMRT) is safe and effective for the treatment of some sinonasal malignancies.
Gang, Peng   +5 more
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Rectal Radiotherapy — Intensity-modulated Radiotherapy Delivery, Delineation and Doses

Clinical Oncology, 2016
The use of intensity-modulated radiotherapy in rectal cancer is attractive in that it may reduce acute and late toxicities and potentially facilitate dose escalation. Intensity-modulated radiotherapy probably has a role in selected patients, but further investigation is required to identify the parameters for selection.
S, Teoh, R, Muirhead
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Intensity modulation methods for proton radiotherapy

Physics in Medicine and Biology, 1999
The characteristic Bragg peak of protons or heavy ions provides a good localization of dose in three dimensions. Through their ability to deliver laterally and distally shaped homogenous fields, protons have been shown to be a precise and practical method for delivering highly conformal radiotherapy.
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Gradients and intensity modulated radiotherapy

Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Cat. No.00CH37143), 2002
A consequence of the advent of intensity modulated radiation therapy (IMRT) is the presence of large dose gradients surrounding the tumor, and the regions at risk (RAR's) near the tumor. Unlike standard radiotherapy, these gradients are not the chance result of a few beam choices, but rather they are strategically placed by the optimization software. A
J.M. Kapatoes   +5 more
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Quality assurance of intensity-modulated radiotherapy

Seminars in Radiation Oncology, 2002
Intensity-modulated radiation therapy (IMRT) requires the use of inverse treatment planning and nonuniform fluence beams delivered by a series of complex radiation portals. The quality assurance procedures for conventional three-dimensional conformal radiation therapy (3D-CRT) have been developed and are in worldwide clinical use, but the more complex ...
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