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Long‐term outcome and pattern of failure for patients with nasopharyngeal carcinoma treated with intensity‐modulated radiotherapy

Head and Neck, 2018
To analyze the long‐term outcome and pattern of failure for patients with nasopharyngeal carcinoma (NPC) after intensity‐modulated radiotherapy (IMRT).
Yun-Ming Tian   +9 more
semanticscholar   +1 more source

Exploration of tradeoffs in intensity-modulated radiotherapy

Physics in Medicine and Biology, 2005
The purpose of this study is to calculate Pareto surfaces in multi-criteria radiation treatment planning and to analyse the dependency of the Pareto surfaces on the objective functions used for the volumes of interest. We develop a linear approach that allows us to calculate truly Pareto optimal treatment plans, and we apply it to explore the tradeoff ...
David, Craft   +2 more
openaire   +2 more sources

Hardware-sensitive optimization for intensity modulated radiotherapy

Physics in Medicine and Biology, 2000
The multileaf collimator (MLC) hardware constraints are usually neglected in the process of intensity-modulated beam optimization. Consequently, it is not always possible to deliver planned beam modulation using dynamic MLC. Beam optimization is significantly diminished if the results must be approximated due to limitations imposed by the delivery ...
P S, Cho, R J, Marks
openaire   +2 more sources

Intensity-modulated radiotherapy of the female breast

Medical Dosimetry, 2002
Current methods for intensity-modulated radiotherapy (IMRT) in breast cancer use forward planning based on equivalent radiological path length to design intensity modulated tangential beams. Compared to conventional tangential techniques, dose reduction of organs at risk is limited using these techniques.
Christoph, Thilmann   +10 more
openaire   +2 more sources

Intensity-modulated radiotherapy: Is xerostomia still prevalent?

Current Oncology Reports, 2005
Conformal radiation with intensity-modulated radiotherapy (IMRT) is a technique that potentially can minimize the dose to salivary glands and thereby decrease the incidence of xerostomia. Precise target determination and delineation is most important when using salivary gland-sparing techniques of IMRT.
Mark S, Chambers   +9 more
openaire   +2 more sources

Intensity-Modulated Radiotherapy – Technology and Clinical Applications

Oncology Research and Treatment, 2002
Intensity-modulated radiotherapy (IMRT) is one of the most important developments in radiooncology of the last years. As an extension of 3D conformal radiotherapy, it provides the possibility of delivering a high radiation dose to the tumor tissue, protecting radiosensible critical organs nearby or even surrounded by the target. This is realized by the
B H, Didinger, W, Schlegel, J, Debus
openaire   +2 more sources

Clinical use of intensity-modulated radiotherapy: part II

The British Journal of Radiology, 2004
Intensity-modulated radiotherapy (IMRT) is a novel conformal radiotherapy technique which is gaining increasing clinical use worldwide. This article aims to summarize the published data pertaining to clinical indications of this therapy for head and neck, central nervous system, and lung tumours. The main indications in head and neck cancer are parotid
M T, Guerrero Urbano, C M, Nutting
openaire   +3 more sources

Endoscopic surgery compared with intensity-modulated radiotherapy in resectable locally recurrent nasopharyngeal carcinoma: a multicentre, open-label, randomised, controlled, phase 3 trial.

The Lancet Oncology, 2021
You-Ping Liu   +16 more
semanticscholar   +1 more source

Conformal radiotherapy, intensity-modulated radiotherapy and image-guided radiotherapy

2008
The aim of radiotherapy is to deliver the desired tumoricidal dose to the intended target as accurately and reliably as possible and avoid unnecessary dose to surrounding normal tissues. This principle was recognized when irradiation was utilized therapeutically over 100 years ago and has been the guiding force for development and refinement of modern ...
openaire   +2 more sources

Intensity-modulated radiotherapy significantly reduces xerostomia compared with conventional radiotherapy

International Journal of Radiation Oncology*Biology*Physics, 2006
Xerostomia is a severe complication after radiotherapy for oropharyngeal cancer, as the salivary glands are in close proximity with the primary tumor. Intensity-modulated radiotherapy (IMRT) offers theoretical advantages for normal tissue sparing. A Phase II study was conducted to determine the value of IMRT for salivary output preservation compared ...
Pètra M, Braam   +3 more
openaire   +2 more sources

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