Results 91 to 100 of about 118,644 (296)

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

open access: yesAdvanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang   +18 more
wiley   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera   +6 more
wiley   +1 more source

Photopolarimetrical properties of coronavirus model particles: Spike proteins number influence

open access: yes, 2021
Coronavirus virions have spherical shape surrounded by spike proteins. The coronavirus spike proteins are very effective molecular mechanisms, which provide the coronavirus entrance to the host cell.
Petrov D.
core  

Direct-drive shock-ignition for the Laser MégaJoule

open access: yesEPJ Web of Conferences, 2013
We present a review of direct-drive shock ignition studies done as an alternative for the Laser MégaJoule (LMJ). One and two dimensional systematic analyses of HiPER-like shock-ignited target designs are performed for the fuel assembly irradiation ...
Canaud B.   +4 more
doaj   +1 more source

A Molecular Shielding Strategy to Develop Low Protein Binding, Renal Clearable Pan‐Cancer Near‐Infrared Probes

open access: yesAdvanced Functional Materials, EarlyView.
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang   +9 more
wiley   +1 more source

Marked point process variational autoencoder with applications to unsorted spiking activities.

open access: yesPLoS Computational Biology
Spike train modeling across large neural populations is a powerful tool for understanding how neurons code information in a coordinated manner. Recent studies have employed marked point processes in neural population modeling. The marked point process is
Ryohei Shibue, Tomoharu Iwata
doaj   +1 more source

Solution‐Processed Thin‐Film Transistors With Tunable Temporal Dynamics for Neuromorphic Computing

open access: yesAdvanced Functional Materials, EarlyView.
Solution‐processed CNT and CNT/P3HT ion‐gated transistors exhibit materials‐defined synaptic timescales: fast CNT devices for high‐frequency spiking and slow hybrid devices for temporal integration. Embedding these dynamics into coupled reservoir‐computing and spiking neural network simulations reveals that a Hybrid‐Reservoir / CNT‐SNN architecture ...
Kevin Schnittker   +5 more
wiley   +1 more source

Geomagnetic spikes on the core-mantle boundary

open access: yesNature Communications, 2017
Rapid and spatially localized geomagnetic field variations around 1000 BC are hard to reconcile with expected field behaviour arising from the core dynamo.
Christopher Davies, Catherine Constable
doaj   +1 more source

Enhancement of Dielectric Breakdown Strength and Recoverable Energy Density in Three‐Dimensional Heterointerfaces on BaTiO3–PbZrO3–PbTiO3 Films via Room‐Temperature Nano‐Clustering

open access: yesAdvanced Functional Materials, EarlyView.
A room‐temperature aerosol deposition process yields multiphase nano‐clustered dielectric capacitors containing discrete BaTiO3, PbZrO3, and PbTiO3 crystals. This architecture creates three‐dimensional heterointerfaces that induce interfacial charge trapping and effectively inhibit breakdown propagation.
Hyunseok Song   +8 more
wiley   +1 more source

Application of Ibuprofen Sodium Dihydrate for Thermochemical Energy Storage

open access: yesAdvanced Functional Materials, EarlyView.
Ibuprofen sodium dihydrate is introduced as a durable organic salt hydrate for low‐temperature thermochemical energy storage, operating within 60°C–110°C with high energy density. At the material level, it delivers ∼99.9% cycling efficiency over 150 cycles without deliquescence, enabled by a dual energy‐storage mechanism coupling dehydration and phase ...
Kavin Chakravarthy Thangaraj   +10 more
wiley   +1 more source

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