Results 221 to 230 of about 698,716 (345)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Analysis of the in-hospital mortality in the tertiary referral department of neonatology and neonatal intensive care. [PDF]

open access: yesSci Rep
Kamianowski A   +5 more
europepmc   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

Left ventricular decompression in paediatric veno‐arterial extracorporeal life support: Reviewing the evidence

open access: yesESC Heart Failure, EarlyView.
Abstract Veno‐arterial extracorporeal life support (VA ECLS) is crucial for neonatal and paediatric patients with severe circulatory collapse but may cause left ventricular (LV) overload, affecting myocardial recovery and causing complications. Evidence on optimal LV decompression strategies in paediatric patients remains limited.
Giacomo Veronese   +21 more
wiley   +1 more source

Association between NT‐proBNP changes and clinical outcomes in paediatric patients with heart failure: Insights from PANORAMA‐HF and PARADIGM‐HF

open access: yesESC Heart Failure, EarlyView.
This post hoc analysis of the PANORAMA‐HF paediatric heart failure trial evaluates the correlation of baseline and clinical changes in NT‐proBNP and clinical outcomes in children with heart failure due to left ventricular systolic dysfunction. This is the first prospective, randomized large‐scale study to demonstrate that changes in NT‐proBNP levels ...
Robert Shaddy   +17 more
wiley   +1 more source

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