Results 151 to 160 of about 6,043,824 (343)

An intensive care record card [PDF]

, 1969
Andrew Doughty
openalex   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Advances in Research on the Release of von Willebrand Factor from Endothelial Cells through the Membrane Attack Complex C5b-9 in Sepsis

Journal of Inflammation Research
Yi Liu,1 Weili Zhao,2 Qingqing Huang,1 Linjun Wan,1 Zongfang Ren,1 Bangting Zhang,1 Chen Han,1 Jin Yang,1 Haoling Zhang,3 Jingjing Zhang4,5 1Department of Critical Care Medicine, The Second Affiliated Hospital of Kunming Medical University, Kunming ...
Liu Y, Zhao W, Huang Q, Wan L, Ren Z, Zhang B, Han C, Yang J, Zhang H, Zhang J   +9 more
doaj  

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

FEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian, Di Liu, Bing Liu, Yu Lan, Jie Zhou   +4 more
wiley   +1 more source

Hemodynamic effects of adjunct arginine vasopressin to norepinephrine in septic shock: insights from a prospective multicenter registry study

Annals of Intensive Care
Background The Surviving Sepsis Campaign guidelines suggest adding arginine vasopressin (AVP) when norepinephrine (NE) doses reach 0.25–0.50 µg/kg/min in septic shock patients.
Max Melchers, Vivienne de Smet, Chrissie Rooijakkers, Jonathan Huising, Wander Vermeulen, Beyza Nur Nisa Köktaş, Karlijn Johanna van de Vusse, Kimia Milani Sabzewar, Shakti Bedanta Mishra, Carina Bethlehem, Dirk P. Boer, Nedim Cimic, Mirella van Duijnhoven, Tim Frenzel, Jordi Liesveld, Gianluca Paternoster, Susanne Stads, Jan J. Weenink, Barbara Festen-Spanjer, Peter Pickkers, Arthur Raymond Hubert van Zanten   +20 more
doaj   +1 more source

Regional organisation of neonatal intensive care in the North-west [PDF]

, 1979
M L Chiswick, P. S. W. Davies, Roger Bate, E H Dryburgh, D Gordon-Nesbitt   +4 more
openalex   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Systemic Inflammatory Response Index Is a More Promising Prognostic Index Than Systemic Immune Inflammation Index in Critically Ill Heart Failure Patients: A Retrospective Cohort Analysis of the MIMIC-IV Database

Vascular Health and Risk Management
Xueqing Wang, Sheng Zhang, Xinxin Wang, Xiaojun Shen, Lei Huang Department of Intensive Care Unit (ICU), Peking University Shenzhen Hospital, Shenzhen, Guangdong, 518036, People’s Republic of ChinaCorrespondence: Xueqing Wang, Department of Intensive ...
Wang X, Zhang S, Wang X, Shen X, Huang L
doaj  

Beyond p‐values: Assessing clinical significance in acupuncture research

Advanced Chinese Medicine, EarlyView.
Abstract In acupuncture randomized controlled trials (RCTs), the proper interpretation of results requires a thorough understanding of key statistical concepts such as p‐value, effect size, and the minimal clinically important difference (MCID). This paper explores the relationships among these metrics and their implications for assessing the clinical ...
Changzhen Gong
wiley   +1 more source