Results 201 to 210 of about 2,158,632 (410)
Alpha‐synuclein RT‐QuIC assay in gastroduodenal and skin biopsies of Parkinson disease patients
Abstract In this study, we compared the value of pathological alpha‐synuclein (αSyn) seed amplification assay (SAA) in gastric and duodenal biopsies with skin biopsies in Parkinson disease (PD) patients with different disease duration. The accuracy of αSyn SAA was 87.7% in skin, 67.4% in duodenum, and 80.0% in gastric biopsies, with significantly ...
Aron Emmi+13 more
wiley +1 more source
Background The objective was to assess the agreement between therapeutic proposals derived from basic critical care echocardiography performed by novice operators in ultrasonography after a limited training (residents) and by experts considered as ...
Marine Goudelin+15 more
doaj +1 more source
Continued Surveillance of Serratia marcescens Infections by Bacteriocin Typing: Investigation of Two Outbreaks of Cross-Infection in an Intensive Care Unit [PDF]
Walter H. Traub
openalex +1 more source
Pediatric, adult, and late onset multiple sclerosis: Cognitive phenotypes and gray matter atrophy
Abstract Objectives We aim to investigate cognitive phenotype distribution and MRI correlates across pediatric‐, elderly‐, and adult‐onset MS patients as a function of disease duration. Methods In this cross‐sectional study, we enrolled 1262 MS patients and 238 healthy controls, with neurological and cognitive assessments.
Ermelinda De Meo+23 more
wiley +1 more source
Estimating the Cost of Informal Care with a Novel Two-Stage Approach to Individual Synthetic Control [PDF]
Informal carers provide the majority of care for people living with challenges related to older age, long-term illness, or disability. However, the care they provide often results in a significant income penalty for carers, a factor largely overlooked in the economics literature and policy discourse.
arxiv
Teaching paediatric critical care medicine to paediatric residents [PDF]
Critical care training during paediatric residency provides an ideal opportunity to learn and refine the skills needed in the early recognition and prompt treatment of the acutely ill paediatric patients. Paediatric critical care medicine is a relatively
Haider, Rizwan+2 more
core +1 more source
Genotype‐function‐phenotype correlations for SCN1A variants identified by clinical genetic testing
Abstract Objective Interpretation of clinical genetic testing, which identifies a potential genetic etiology in 25% of children with epilepsy, is limited by variants of uncertain significance. Understanding functional consequences of variants can help distinguish pathogenic from benign alleles.
Andrew T. Knox+6 more
wiley +1 more source
Right‐sided vagus nerve stimulation: Worldwide collection and perspectives
Abstract Objective Vagus nerve stimulation (VNS) is an established therapy for drug‐resistant epilepsy (DRE) and is indicated for implantation on the left vagus nerve‐only. In rare cases right‐sided VNS may be the only option. With only seven published cases in the literature, data on safety and effectiveness of right‐sided VNS is very limited ...
Marc Zanello+31 more
wiley +1 more source
Abstract Objective We measured clinical and quantitative MRI outcome measures in CMT1A to assess long‐term responsiveness, establish longitudinal validity and assess MRI as a bridging biomarker. Methods Twenty patients with CMT1A and 20 matched controls underwent MRI, myometry and clinical assessments up to four times over mean 4‐year follow‐up ...
Matthew R. B. Evans+8 more
wiley +1 more source