Results 101 to 110 of about 113,262 (301)

ER‐phagy Activation by AMFR Attenuates Cardiac Fibrosis Post‐Myocardial Infarction via mTORC1 Pathway

open access: yesAdvanced Science, EarlyView.
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang   +10 more
wiley   +1 more source

The Turkish Validity Reliability Study of the Neonatal Braden Q Pressure Ulcer Risk Assessment Scale

open access: yesJournal of Behçet Uz Children's Hospital, 2020
INTRODUCTION: ressure sore is a common care problem in intensive care units which prolongs hospital stay, increases mortality and treatment costs. Validity and reliability study of neonatal Braden Q scale, which is developed for the neonatal period, has ...
Nalan Yalçın Baltacı   +8 more
doaj   +1 more source

Impact of managed clinical networks on neonatal care in England : a population-based study [PDF]

open access: yes, 2012
Objective: To assess the impact of reorganisation of neonatal specialist care services in England after a UK Department of Health report in 2003. Design: A population-wide observational comparison of outcomes over two epochs, before and after the ...
Gale, C.   +4 more
core  

NICU Infants & SNHL: Experience of a western Sicily tertiary care centre [PDF]

open access: yes, 2019
Introduction: The variability of symptoms and signs caused by central nervous system (CNS) lesions make multiple sclerosis difficult to recognize,Introduction: This study adds the evaluation of the independent etiologic factors that may play a role in ...
Abita P   +6 more
core   +1 more source

Single‐Cell Transcriptome Profiling Reveals Conserved IFNγ‐IL8 Signaling‐Induced Antibacterial Neutrophil States during Bacterial Infection

open access: yesAdvanced Science, EarlyView.
SummaryThis study constructs a single‐cell immune atlas of Nile tilapia across multiple time points during Streptococcus agalactiae infection, revealing dynamic immune cell responses and subtype transitions. It identifies a conserved IFNr‐STAT1‐IL8 axis driving il8+ neutrophils activation and antibacterial function, supported by cross‐species ...
Xue Zhai   +14 more
wiley   +1 more source

A paediatric telecardiology service for district hospitals in south-east England: an observational study. [PDF]

open access: yes, 2008
The attached article is a Publisher version of the final published version which may be accessed at the link below. Copyright © 2010 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Dowie, R   +6 more
core   +2 more sources

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

open access: yesAdvanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez   +20 more
wiley   +1 more source

Origins of neonatal intensive care in the UK [PDF]

open access: yes, 2001
Chaired by Professor Robert Boyd, this seminar reviewed the development and changes in care of the newborn in the UK over the past 50 years. Advances in techniques were described, such as mechanical ventilation, total parenteral nutrition and continuous ...

core  

Tendinopathy: The Interplay between Mechanical Stress, Inflammation, and Vascularity

open access: yesAdvanced Science, EarlyView.
This review explores the complex and self‐reinforcing cycle of mechanical stress, inflammation, and altered vascularity in tendinopathy—a common, painful tendon disorder. It integrates current findings on cellular, molecular, and biomechanical mechanisms, highlighting how mechanical overload, inflammatory signals, and abnormal blood vessel behavior ...
Renate Gehwolf   +5 more
wiley   +1 more source

THE COMPARATIVE ANALYSIS OF MICROBIOLOGICAL MONITORING IN NEONATAL INTENSIVE CARE UNITS IN KRASNIDAR REGIONAL CLINICAL HOSPITAL №2

open access: yesКубанский научный медицинский вестник, 2018
Aim. To compare proportion of different microorganisms in neonatal intensive care units and to assess bacterial susceptibility to antimicrobial agents.Materials and methods.
N. E. SHABANOVA   +4 more
doaj   +1 more source

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