Results 141 to 150 of about 47,746 (268)

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Corrigenda: Pain, Agitation, Delirium, and Iatrogenic Withdrawal Syndrome Management in Children Who Are Critically Ill: Protocol for a European Clinical Practice Guideline Using the Grading of Recommendations Assessment, Development, and Evaluation Approach. [PDF]

JMIR Res Protoc
MacDonald I, Cavin-Trombert A, Jaques C, De Clifford-Faugère G, De Cock PA, de Wildt SN, Dmytriiev D, Engel J, Fazio PC, George S, Goyer I, Harðardóttir A, Harris J, Horváth K, Ista E, Mencía S, Metsvaht T, Mondardini MC, Oualha M, Perez MH, Pietrzkiewicz K, Sperotto F, Wyness B, Yalındağ N, ESPNIC Nursing and Allied Healthcare Professionals Section, ESPNIC Pharmacology Section, Amigoni A, Ramelet AS.   +27 more
europepmc   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Delivery Routes and Anesthesia Affect Cord Blood NGF, BDNF, and Neonatal Outcomes

Journal of Clinical Laboratory Analysis, EarlyView.
Nerve growth factor (NGF) and brain‐derived neurotrophin (BDNF) play a role in brain maturation. Cord blood values do not differ between vaginal delivery and CS cases. In CS cases with spinal anesthesia, high BDNF and NGF values were associated with high cord blood pH and APGAR scores.
Şükran Doğru, Huriye Ezveci, Fikriye Karanfil Yaman, Pelin Bahçeci, Zeynep Şenol, İbrahim Kılınç, Kazım Gezginç   +6 more
wiley   +1 more source

Detection of placenta accreta spectrum and prediction of adverse perinatal outcomes in pregnant women with placenta previa using ultrasonography and magnetic resonance imaging: A retrospective cohort study. [PDF]

PLoS One
Kim S, Jung YJ, Zhang HS, Yoon JH, Choi S, Kwon H, Kwon JY, Kim YH, Lee J.   +8 more
europepmc   +1 more source

Impact of Different Pre‐Dilution Methods on Routine Blood Test Results: A Study With Sysmex XN‐1000

Journal of Clinical Laboratory Analysis, EarlyView.
The wet wipe method demonstrated excellent consistency with automated injection across all five parameters and is recommended as the preferred technique when sample volume is limited. ABSTRACT Objectives To compare three manual pre‐dilution procedures with the automated undiluted mode on the Sysmex XN‐1000 analyzer and to identify an optimal standard ...
Lingsong Wu, Mengzhe Qin, Zhe Xing, Fengli Jiang, Sien Zhan, Jintian Hu   +5 more
wiley   +1 more source

Swedish Intensive Care Physicians' Attitudes Towards Withholding or Withdrawing Life-Sustaining Treatment in Critically Ill Children. [PDF]

Acta Anaesthesiol Scand
Ahlerup M, Malmgren J, Castellheim AG, Holmén J, Ingemansson O, Sandman L, Hergès HO, Block L.   +7 more
europepmc   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Impact of a national nirsevimab programme on critical care transport of babies with bronchiolitis: a retrospective observational study. [PDF]

Arch Dis Child
Moore T, Afridi A, Aminudin NH, Gibbons C, Grant O, Fucikova H, Moore CM.   +6 more
europepmc   +1 more source

Sense of Coherence in the Perinatal Period: A Longitudinal Growth Mixture Modeling Analysis

Journal of Clinical Psychology, EarlyView.
ABSTRACT Objectives Previous studies have established that higher Sense of Coherence (SoC) predicts lower pregnancy‐specific distress, fewer delivery complications, and increased birth satisfaction. However, less is known about how SoC typically changes over pregnancy, birth, and postnatally and the risk factors and protective factors contributing to ...
Kelsey Perrykkad, Stuart Watson, Andrew J. Lewis, Marinus Van IJzendoorn, Megan Galbally   +4 more
wiley   +1 more source