Advanced Science, EarlyView.In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng +17 more
wiley +1 more source
Cultura de segurança do paciente em unidades de terapia intensiva neonatal [PDF]
, 2013 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2013.A cultura de segurança do paciente é discutida mundialmente sendo considerada um elemento essencial
Tomazoni, Andréia
core
Improvement in neonatal intensive care unit care: a cluster randomised controlled trial of active dissemination of information. [PDF]
, 2011 BACKGROUND: Research findings are not rapidly or fully implemented into policies and practice in care. OBJECTIVES: To assess whether an 'active' strategy was more likely to lead to changes in policy and practice in preterm baby care than traditional ...
Allen, Elizabeth +11 more
core +1 more source
Neonatal Nightingales: Live Parental and Neonatal Nurse Infant-Directed Singing as a Beneficial Intervention for the Health and Development of Infants in Neonatal Care [PDF]
, 2012 A Project submitted in partial fulfilment of the assessment requirements for the award of MA MusicologyIt is the aim of this study to establish live neonatal nurse and parental infant-directed singing as a potentially efficacious intervention that is ...
Barnell, Ruby
core +3 more sources
Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium
Advanced Science, EarlyView.Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed +12 more
wiley +1 more source
Virulence potential of enterobacteriaceae isolated from neonatal enternal feeding tubes [PDF]
, 2013 In recent years, there has been a rise in the incidence of neonatal infections due to Enterobacteriaceae including Escherichia coli, Enterobacter, Klebsiella and Serratia spp.
Alkeskas, AA
core
Impact of prematurity on long-stay paediatric intensive care unit admissions in England 2008-2018
BMC Pediatrics, 2023 Background Survival following extreme preterm birth has improved, potentially increasing the number of children with ongoing morbidity requiring intensive care in childhood.
Tim J. van Hasselt +6 more
doaj +1 more source
Advanced Science, EarlyView.This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun +12 more
wiley +1 more source
Quality of Nurses' Performance Regarding Parenteral Nutrition at Neonatal Intensive Care Units [PDF]
Egyptian Journal of Health Care, 2018 Background: Nurses play a crucial role at neonatal intensive care, as they are responsible for administering parenteral nutrition to critically ill neonates.
Noura Abdel-Fattah Mahmoud +2 more
doaj +1 more source
Advancing Neurologic Care in the Neonatal Intensive Care Unit With a Neonatal Neurologist [PDF]
Journal of Child Neurology, 2012 Neonatal neurology is a growing subspecialty area. Given the considerable amount of neurologic problems present in the neonatal intensive care unit, a neurologist with expertise in neonates is becoming more important. We sought to evaluate the change in neurologic care in the neonatal intensive care unit at our tertiary care hospital by having a ...
Sarah B, Mulkey +1 more
openaire +2 more sources