Results 241 to 250 of about 340,222 (309)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

open access: yesAdvanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode   +16 more
wiley   +1 more source

A dramatic case: fatal air embolism due to intraosseous puncture. [PDF]

open access: yesInt J Emerg Med
Muench M   +4 more
europepmc   +1 more source

Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation

open access: yesAdvanced Materials, EarlyView.
Liquid metal‐based microrobots combine magnetic steering, intrinsic X‐ray visibility and softness, to navigate blood vessels even against flow. Under clinically relevant magnetic fields, liquid metal microrobots roll along vessel walls, cross endothelial barriers, and accumulate in target tissues.
Xiaohui Ju   +7 more
wiley   +1 more source

Stability of arterial blood gas samples after delayed analysis and mechanical stress. [PDF]

open access: yesPLoS One
Gutermuth M   +4 more
europepmc   +1 more source

Impact of Anode to Cathode Crossover in Lithium‐metal Batteries With High‐Nickel Cathodes

open access: yesAdvanced Materials, EarlyView.
Anode‐to‐cathode chemical crossover is identified as a critical degradation mechanism in lithium‐metal batteries. Full‐cell experiments with high‐Ni layered oxide cathodes and localized high‐concentration electrolytes reveal accelerated cathode impedance growth and CEI thickening driven by lithium‐metal anodes. The findings underscore the importance of
Zezhou Guo   +2 more
wiley   +1 more source

Multiphysics‐Driven Assembly of Biomimetic Vesicles

open access: yesAdvanced Materials, EarlyView.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko   +16 more
wiley   +1 more source

Energy‐Efficient, Sustainable Cascade Glucose Electrooxidation into Glucaric Acid

open access: yesAdvanced Materials, EarlyView.
This study presents a tandem system that efficiently converts glucose into glucaric acid while generating renewable electricity. By decoupling the oxidation process into two cascaded steps, the system achieves an overall 90% Faradaic efficiency and 80% conversion efficiency at ∼0.6 VRHE, significantly reducing energy consumption compared to traditional
Mingming He   +15 more
wiley   +1 more source

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