Results 111 to 120 of about 3,151,694 (416)
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring+6 more
wiley +1 more source
Intentional movement is an internally driven process that requires the integration of motivational and sensory cues with motor preparedness. In addition to the motor cortical-basal ganglia circuits, the limbic circuits are also involved in the ...
Sule Tinaz+12 more
doaj +1 more source
Zero-shot User Intent Detection via Capsule Neural Networks [PDF]
User intent detection plays a critical role in question-answering and dialog systems. Most previous works treat intent detection as a classification problem where utterances are labeled with predefined intents. However, it is labor-intensive and time-consuming to label users' utterances as intents are diversely expressed and novel intents will ...
arxiv
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
Shared Agency Without Shared Intention [PDF]
The leading reductive approaches to shared agency model that phenomenon in terms of complexes of individual intentions, understood as plan-laden commitments. Yet not all agents have such intentions, and non-planning agents such as small children and some
Asarnow, Samuel
core
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Determinants of online shopping intention [PDF]
The internet has become a key medium for the purchase of products and services in virtual markets and has effectively linked all countries and business. It has been estimated that the internet market is worth $300 billion in 1995.
Meor Ahmad, Siti Salwani+1 more
core
Do self-reported intentions predict clinicians behaviour: a systematic review. [PDF]
Background: Implementation research is the scientific study of methods to promote the systematic uptake of clinical research findings into routine clinical practice.
A Walker+39 more
core +4 more sources
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang+2 more
wiley +1 more source
Exploring the latitude of attitude: Intentions to breastfeed among adolescents in Lebanese schools. [PDF]
School-based breastfeeding education (SBBE) may help improve breastfeeding rates in the long-term by targeting children and adolescents' knowledge, attitudes, skills, and intentions. Breastfeeding rates in Lebanon are suboptimal.
Abou Jaoudeh, Maya+5 more
core