Results 191 to 200 of about 548,323 (297)

Intention to treat analysis is related to methodological quality [PDF]

, 2000
Miguel Ruiz‐Canela
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Analysis of the mediating effect of occupational burnout on the relationship between emotional labor and turnover intention among obstetric nurses. [PDF]

Front Public Health
Lv X, Ding Z, Wang T, Zhang M.
europepmc   +1 more source

Active Understanding of Human Intention by a Robot through Monitoring of Human Behavior.

, 1995
Tomomasa Sato, Yoshifumi Nishida, Junri Ichikawa, Yotaro HATAMURA, Hiroshi Mizoguchi   +4 more
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Predicting the Determinants of Colorectal Cancer Screening Behaviors Using Protection Motivation Theory: A Cross-Sectional Partial Least Squares Structural Equation Modeling Analysis. [PDF]

Health Sci Rep
Gholian-Aval M, Behrouzi B, Jamali J.
europepmc   +1 more source

Department of Water Resources' notice of intention to file an application for certification of DWR Bottle Rock. Final report

, 1979

openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Relationship among service accessibility, social norms, herpes zoster vaccination intention of middle-aged and older adults in Chongqing: mediating role of perceived usefulness. [PDF]

Front Public Health
Deng Y, Wang T, Yu L, Fu X, Luo Y, Chen F.   +5 more
europepmc   +1 more source

Informal Caregivers and the Intention to Hasten AIDS-Related Death

, 1998
Molly Cooke, Linda Gourlay, Laurence Collette, Alicia Boccellari, Margaret A. Chesney, Susan Folkman   +5 more
openalex   +1 more source