Results 201 to 210 of about 3,151,694 (416)

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Possible Intentions and the Doctrine of Double Effect [PDF]

open access: yes, 2019
Under the standard formulation of the Doctrine of Double Effect, an act is permissible only if it is the result of an intention to do good and not the result of an intention to do bad.
Fruge, Christopher
core  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Derrida and meaning : the problem of authorial intention : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in English at Massey University [PDF]

open access: yes, 1985
This thesis examines Jacques Derrida's deconstructive critique of the logocentric concept of meaning and.proposes that Derrida's critique maintains the importance of authorial intention for literary critical practice.
Molloy, Harvey Lees
core  

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Personal characteristics, occupational stress and turnover intentions among school teachers in Negeri Sembilan, Malaysia [PDF]

open access: yes, 2007
Stress is considered as a serious problem in the modern workplace. This paper summarizes occupational stress and turnover intentions experienced by secondary school teachers in the state of Negeri Sembilan, Malaysia.
Abdullah, Muhammad Madi   +3 more
core  

Home - About - Disclaimer - Privacy