Results 41 to 50 of about 806,998 (269)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The impact of supplementary narrative-based information on colorectal cancer screening beliefs and intention [PDF]

open access: yes, 2015
Background: The potential benefits of colorectal cancer screening are limited by low uptake. This study tested whether providing narrative accounts of the colorectal cancer (CRC) screening experience positively affected beliefs about CRC screening and ...
McGregor, Lesley M   +22 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Voluntariness and Intention [PDF]

open access: yesJurisprudence, 2016
I am very grateful to the editors of Jurisprudence for proposing this symposium, and to Maria Alvarez, Erasmus Mayr, Dennis Patterson and Assaf Sharon for taking the time and trouble to write about Action, Knowledge, and Will. I have not been able to address every argument they present, and every question they raise, because of the limitations of space,
openaire   +2 more sources

Intention-Aware Multiagent Scheduling

open access: yes, 2020
The Belief Desire Intention (BDI) model of agency is a popular and mature paradigm for designing and implementing multiagent sys- tems. There are several agent implementation platforms that follow the BDI model.
Brian Logan (15470308)   +3 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The factors driving continuance intention to online shopping (e-loyalty): behaviour differences in the case of Saudi Arabia [PDF]

open access: yes, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University LondonThis study proposes a model of e-shopping continuance intentions that incorporate the revised technology acceptance model and expectation confirmation
Al-maghrabi, Talal Ahmed Abdullah
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Intention-to-treat analysis for further secondary outcomes after 24 months.

open access: yes, 2019
Intention-to-treat analysis for further secondary outcomes after 24 months.
Sylvia Schulz-Rothe (3558641)   +10 more
core   +1 more source

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