Results 101 to 110 of about 48,981 (306)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The Effect of Trust, Competitive Price, and Application Quality on Repurchase Intention of Online Travel Agent Traveloka [PDF]

, 2021
Repurchase intention is included in post-purchase behavior, so it becomes an important topic to be investigated. This study aims to determine the effect of trust, competitive prices, and application quality on repurchase intention in Traveloka online ...
HUSNAWIYAH, Dewi, AFANDI, Mochammad Farid, YULISETIARINI, Diah   +2 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The factors that influence travel intention among youth in Penang [PDF]

, 2021
The purpose of this research is to examine the relationship of education, culture, transportation and travel intention among youth in Penang. The main objective for this research is to investigate the factor that influence travel intention among youth in
Ainul Hayati Mohd Khairi,, Elly Maya Masnida Othman,, Nur Izyani Abd Rahim,, Siti Nur Balqis Che Azman,   +3 more
core  

THE RELATION BETWEEN EMOTIONAL LABOR, JOB BURNOUT AND INTENTION TO TURNOVER: A RESEARCH ON TRAVEL AGENCY WORKERS [PDF]

Economy and Sociology, 2015
The aim of this study is to show the relation between emotional labor, job burnout and intention to turnover of travel agency workers, and to develop appropriate suggestions in the light of obtained findings.
Lokman TOPRAK, Gülseren ÖZALTAŞ SERÇEK, Ayhan KARAKAŞ, Sadık SERÇEK   +3 more
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

How subjective knowledge influences intention to travel [PDF]

This study analyzes tourist intention in the early phase of the tourists' decision-making process. Through correlations and web-experiments, we trace subjective knowledge through the tourists' accumulation of diagnostic cues inherent in a destination and
Tassiello, V, Tillotsono, JS
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

The impact mechanism of social network information on tourism travel: an empirical analysis based on internet celebrity cities

Humanities & Social Sciences Communications
Social networks have profoundly influenced human thinking and behaviour patterns and have effectively promoted the development and evolution of the urban tourism economy.
Jian Chen, Xiaotong Wu, Yi Luo, Keliang Liu   +3 more
doaj   +1 more source

The Impact of Digital Content Marketing on Travel Intentions to Tourist Destinations: A Proposed Model Based on Perceived Value and Loyalty

BAR: Brazilian Administration Review
Objective: this study analyzes the antecedents of the intention to travel to tourist destinations using digital content marketing (DCM) based on the advertising value theory and the brand loyalty theory from an attitudinal perspective.
Jackson de Souza, Sérgio Marques Júnior, Luiz Mendes-Filho   +2 more
doaj   +1 more source