Results 221 to 230 of about 378,463 (268)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Attitudes and beliefs towards contraception and future intention to use a method among women in refugee settlements in Uganda. [PDF]

open access: yesContracept Reprod Med
Kisaakye P   +12 more
europepmc   +1 more source

Factors influencing perceived benefits and behavioral intention to use mental health chatbots among professional employees: an empirical study. [PDF]

open access: yesFront Digit Health
Naji GMA   +8 more
europepmc   +1 more source

The Effects of Facebook on Use Intention

International Journal of Innovation in the Digital Economy, 2022
Given the changes of time and advances in technology, cyberspace communities have gradually become the platform of content and information integration. Internet users enhances their interpersonal relationships and establish themselves multiple identities on the Internet in order to gain a sense of self-fulfilling achievement.
Yi Fen Chen   +2 more
openaire   +1 more source

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