Results 111 to 120 of about 88,049,012 (304)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Determinants of adults' intention to vaccinate against pandemic swine flu [PDF]

, 2011
This article has been made available through the Brunel Open Access Publishing Fund.This article has been made available through the Brunel Open Access Publishing Fund.Background: Vaccination is one of the cornerstones of controlling an influenza ...
Myers Lynn B, Lynn B Myers, Goodwin, R, Goodwin Robin, Myers, LB, Robin Goodwin   +5 more
core   +2 more sources

T The Effect of Perceived Ease and Benefits on Intention and Behavior to use E-Learning Islamic Higher Education

Journal of Education Technology
This study aims to examine the effect of perceived benefits and perceived ease of use on the intention and behavior of using e-learning at State Islamic University (UIN) Walisongo Semarang.
Syaiful Bakhri
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Understanding Generation Z’s Intention to Use Digital Banks: The Role of Perceived Usefulness and Attitude

Danadyaksa
The rapid growth of digital banking services has transformed the financial industry, particularly in attracting younger consumers who are highly dependent on technology.
Nyayu Khalilah Putri, Sulastri Sulastri, Mohamad Adam, Yuliani Yuliani   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Antecedents of Intention to Use E-Learning

MATEC Web of Conferences, 2018
This study investigates the effect of Attitude toward e-learning, Facility condition, and Personalization on intention to use e-learning. theory of plan behaviour is used to understand the antecedents of intention to use e-learning. Using academic staffs
Khairudin, Herawati Susi, Ilona Desi, Zaitul   +3 more
doaj   +1 more source

Investigating Students' Intention to Use M-Learning

International Journal of Information and Communication Technology Education
Mobile learning (M-learning) has become a crucial tool for both students and educators. The unified theory of acceptance and use of technology (UTAUT), the technology acceptance model (TAM), and outside factors were all included in this study's integrative review approach to examine the variables affecting university students' intention to use M ...
openaire   +1 more source