Results 201 to 210 of about 144,079 (272)

Intentional Naproxen Overdose Causing Metabolic Acidosis: A Case Report. [PDF]

Cureus
Falatovich B, Isom B.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

In a Bind: Artificial Cranial Deformation in the Americas [PDF]

, 2014
Fehir, Aaron
core   +1 more source

Self-reflection, sense of agency, and underlying neural correlates: A pilot study. [PDF]

PLoS One
Gupta KV, Beuria J, Vijanapalli LK, Sethi A, Behera L.   +4 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Inhibition of intentional binding by an additional sound presentation

Inhibition of intentional binding by an additional sound presentation
When a voluntary action is followed by an effect after a short delay, the time distance between the action and its effect is perceived to be shorter than the actual time distance. This phenomenon is known as intentional binding (IB). We investigated the influence of presentation of an additional effect on IB between the action and the target effect ...
openaire  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Deficient Visuospatial Incidental and Intentional Memory in Cognitively Healthy Middle-Aged First-Degree Descendants of Alzheimer's Disease Patients. [PDF]

Brain Sci
Álvarez-Huante CG, Rincón-Ortega MF, Palomares-Vallejo EJ, Téllez-Anguiano ADC, Junco-Muñoz ML, López-Vázquez MÁ, Olvera-Cortés ME.   +6 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Potassium Overdose in Patient with Chronic Kidney Disease on Losartan: A Case Report. [PDF]

Clin Pract Cases Emerg Med
Naseem A, Schoenborn M, Scheidler J, Barclay WH, Volk G.   +4 more
europepmc   +1 more source