Results 161 to 170 of about 367,581 (336)

Context and Motive: Evidence and Intentional Explanation in International Relations

, 2011
Joseph O’Mahoney
openalex   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Kindergarten Children Demonstrating Numeracy Concepts through Drawings and Explanations: Intentional Teaching within Play-based Learning

, 2016
Philemon Chigeza, Reesa Sorin, James Cook Univerisity   +2 more
openalex   +2 more sources

Inattention and Hyperactivity Symptom Dimensions of ADHD Differentially Moderate the Relationship Between Concurrent Attention States and Affective Valence. [PDF]

J Atten Disord
Ain Y, Rai S, Galbraith A, Buerkner J, Andrews-Hanna JR, Callahan BL, Kam JWY.   +6 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Causal explanation, intentionality, and prediction: Evaluating the Criticism of "Deductivism" [PDF]

, 2001
Carsten Allan Koch
openalex  

Self-Concept Clarity and AI Anxiety in Graduate Students: Mediating Roles of Intentional Self-Regulation and Perceived Stress and Moderating Role of Intolerance of Uncertainty. [PDF]

Behav Sci (Basel)
Li Q, Chen Y, Zhang M, Zhang J, Fu Z, Ye F.   +5 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

The Medicolegal Implications of Functional Neurological Disorder. [PDF]

Semin Neurol
Yogarajah M, Teodoro T, Agrawal N.
europepmc   +1 more source