Results 31 to 40 of about 158,845 (295)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Hypoiconicity as Intentionality

open access: yesPhilosophies, 2022
The paper analyses Peirce’s hypoiconicity through the lens of Husserlian intentionality. Peirce’s triple structure of hypoiconicity as resemblance relation, diagrammatical reasoning and metaphoric displacement is shown to require intentional acts in its ...
Horst Ruthrof
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Brentano on Intentionality [PDF]

open access: yes, 2017
Brentano’s account of what he called intentionale Inexistenz — what we now call intentionality — is without question one of the most important parts of his philosophy, and one of the most influential ideas in late 19th-century philosophy.
Crane, Tim
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Collective Intentionality and Causal Powers

open access: yesJournal of Social Ontology, 2015
Bridging two traditions of social ontology, this paper examines the possibility that the concept of collective intentionality can help to explain the mechanisms underpinning the causal powers of some social entities.
Dave Elder-Vass
doaj   +2 more sources

Peculiarities of the Intentionality of Teenagers Studying in the a Specialized and Basic Education Programs

open access: yesПсихологическая наука и образование (2007. Online), 2015
The article presents the results of an empirical study of intentionality of adolescents studying in the a specialized and basic educational program. Intentionality of the individual is considered in two aspects: time (temporal) and content.
Kondratyev M.D.,
doaj   +1 more source

The role of prior exposure in the likelihood of adopting the Intentional Stance toward a humanoid robot

open access: yesPaladyn, 2023
One of the key questions in human–robot interaction research is whether humans perceive robots as intentional agents, or rather only as mindless machines. Research has shown that, in some contexts, people do perceive robots as intentional agents. However,
Roselli Cecilia   +3 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Does Separating Intentionality From Mental Representation Imply Radical Enactivism?

open access: yesFrontiers in Psychology, 2018
Traditionally, intentionality is regarded as that feature of all and only mental states – paradigmatically beliefs and desires – in virtue of which they are directed at or are about something.
Tobias Schlicht
doaj   +1 more source

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