Results 151 to 160 of about 1,479,679 (365)
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
INTENTIONS AND MOTIVATIONS TO REVISIT NATURAL HERITAGE SITES [PDF]
, 2022 Laurentiu Florentin Stoenică
openalex +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
To include or not to include – the impact of an inclusive leadership style on turnover intentions [PDF]
L.B. Seck, Margret Borchert
openalex +1 more source
The impact of sexual harassment on job satisfaction, turnover intentions, and absenteeism: findings from Pakistan compared to the United States [PDF]
, 2014 Rebecca S. Merkin, Muhammad Kamal Shah
openalex +1 more source
Entrepreneurial intentions: The influence of organizational and individual factors [PDF]
An individual's intent to pursue an entrepreneurial career can result from the work environment and from personal factors. Drawing on the entrepreneurial intentions and the person–environment (P–E) fit literatures, and applying a multilevel perspective ...
Foo, Maw Der +3 more
core +1 more source
Entrepreneurship Education and Entrepreneurial Intention: Perspectives on Institutional Theory [PDF]
, 2019 Entrepreneurial intentions have been considered a critical element understanding the formation of new venture creations that have been seen in creating jobs and economic growth in a country.
Liang, Wen-ke, Wannamakok, Wisuwat
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
, 2018 In this paper, I argue that joint action permits a certain degree of luck. The cases I have in mind exhibit the following structure: each participant believes that the intended ends of each robustly support the joint action.
Schönherr, Julius
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source