Results 71 to 80 of about 151,437 (268)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Governance of electoral preferences, consensus and voting intention

Tecnociencia Chihuahua, 2019
The political system in which it is possible to observe the similarities and differences between groups for and against presidential candidates based on processes of negotiation, mediation, conciliation and arbitration around the management and ...
Enrique Martínez Muñoz, María de Lourdes Morales Flores, Cruz García Lirios   +2 more
doaj  

Fertility intentions, current practices and associated factors among co-habiting women in a medical officer of health area in the district of Nuwara Eliya

Journal of the College of Community Physicians, 2018
Background:Identifying the prevailing intentions and practices related to fertility among females is important in promoting pre-pregnancy care service delivery to eligible families.Objective:To describe the fertility intentions regarding conception ...
Onali B. W. Rajapakshe, Nirosha Lansakara   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Distal outcomes of communal goal mismatch: a longitudinal study of underrepresented students in STEM

Frontiers in Psychology
Using the goal congruity framework, this longitudinal study investigated whether communal goal mismatch predicted distal outcomes of STEM intentions, STEM identity, and a sense of belonging among students pursuing degrees in STEM fields.
Ashley Bonilla, Wesley Schultz, Anna Woodcock, Paul R. Hernandez   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Predictors of Recycling Intentions among the Youth: A Developing Country Perspective

Recycling, 2018
India is currently facing a mounting challenge related to municipal waste management, due to an increasing urban population, and their high consumption lifestyles.
Pradipta Halder, Harminder Singh
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Shared intention and personal intentions [PDF]

Philosophical Studies, 2009
This article explores the question: what is it for two or more people to intend to do something in the future? In a technical phrase, what is it for people to share an intention? Extending and refining earlier work of the author’s, it argues for three criteria of adequacy for an account of shared intention (the disjunction, concurrence, and obligation ...
openaire   +4 more sources