Results 21 to 30 of about 323 (122)

Sevoflurane Inhibits Layer 5 Pyramidal Neurons via Kv1.2‐Dependent Modulation of Subthreshold Currents

open access: yesJournal of Neurochemistry, Volume 170, Issue 1, January 2026.
General anesthetics suppress cortical activity, but their cellular mechanisms remain unclear. We investigated how the volatile anesthetic sevoflurane affects layer 5 pyramidal neurons in the auditory cortex. Using patch‐clamp recordings and computational modeling, we found that low‐dose sevoflurane reduces neuronal firing through Kv1.2 channel ...
Aelton S. Araujo   +4 more
wiley   +1 more source

UEG Week 2022 Moderated Posters

open access: yes, 2022
United European Gastroenterology Journal, Volume 10, Issue S8, Page 185-472, October 2022.
wiley   +1 more source

Revisión. Peces como biofactorías: sistemas genéticos inducibles y de inserción dirigida

open access: yes, 2003
The production of recombinant human proteins for pharmaceutical products in transgenic animals is progressingslowly. Compared to mammals, fish offer easier genetic manipulation since they produce hundreds of eggs per femaleand because of the independent ...
Estepa, A.   +3 more
core   +1 more source

In Vitro Monitoring of Taste Compound Release During Chewing According to Process‐Related Parameters of the Food

open access: yesJournal of Texture Studies, Volume 56, Issue 6, December 2025.
Two applications of in vitro studies on taste compound release and food bolus formation using a chewing simulator are presented. The addition of oil appears to promote the release of taste compounds from corn grit snacks. For cooked carrots, the greater variability and inhomogeneous distribution observed with the plate salting method account for the ...
Raphaël Monod   +10 more
wiley   +1 more source

UEG Week 2022 Poster Presentations

open access: yes, 2022
United European Gastroenterology Journal, Volume 10, Issue S8, Page 473-1092, October 2022.
wiley   +1 more source

El complejo de Vaska y la química organometálica

open access: yesNOVASINERGIA, 2020
En 1961, Lauri Vaska y John W. DiLuzio publicaban un importante trabajo en el área de los complejos organoiridio, la síntesis y caracterización del trans-clorocarbonilbis (trifenilfosfina-κP)iridio(I), trans-[IrCl(CO)(PPh3)2], un compuesto ...
Ricardo R. Contreras   +2 more
doaj   +1 more source

Contribución al estudio de la composición alcaloídica de Narcissus primigenius [PDF]

open access: yes, 1991
Tesi de Llicenciatura per a la obtenció del Grau de Farmàcia. Facultat de Farmàcia. Universitat de Barcelona. Director: Bastida Armengol, Jaume; Codina Mahrer, Carles. 1991.Dentro de los productos naturales de origen vegetal se encuentran los alcaloides,
Bergoñón Fuster, Salvador
core  

Exposure‐Efficacy Analysis and Dopamine D2 Receptor Occupancy in Adults with Schizophrenia after Treatment with the Monthly Intramuscular Injectable Risperidone ISM

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 3, Page 350-360, March 2025.
Abstract Dopamine D2 receptor occupancy (D2RO) significantly influences the clinical effectiveness and safety of many antipsychotic drugs. Maintaining a D2RO range of 65%‐80% provides the best antipsychotic effects while minimizing adverse reactions.
Andreas Lindauer   +8 more
wiley   +1 more source

Abstract Book for the 27th Congress of the European Hematology Association

open access: yes, 2022
HemaSphere, Volume 6, Issue S3, Page 1-4130, June 2022.
wiley   +1 more source

A p75 neurotrophin receptor‐sparing nerve growth factor protects retinal ganglion cells from neurodegeneration by targeting microglia

open access: yesBritish Journal of Pharmacology, Volume 181, Issue 23, Page 4890-4919, December 2024.
Abstract Background and Purpose Retinal ganglion cells (RGCs) are the output stage of retinal information processing, via their axons forming the optic nerve (ON). ON damage leads to axonal degeneration and death of RGCs, and results in vision impairment. Nerve growth factor (NGF) signalling is crucial for RGC operations and visual functions.
Laura Latini   +20 more
wiley   +1 more source

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