Results 31 to 40 of about 4,549 (218)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi   +13 more
wiley   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Aplicación del principio del interés superior de la niñez y la adolescencia en la participación política de adolescentes de Lima Metropolitana

open access: yesBoletín Mexicano de Derecho Comparado
El derecho a la participación política de adolescentes es un derecho fundamental, el cual es vulnerado pese a que goza de protección constitucional. Ello, debido a la errónea interpretación del principio del interés superior de la niñez y la adolescencia,
Lesly Paola Diaz Aguilar   +2 more
doaj   +1 more source

El interés superior del niño y el razonamiento jurídico

open access: yesProblema: Anuario de Filosofía y Teoría del Derecho, 2013
El presente artículo reflexiona sobre el papel que desempeña el principio del “interés superior del niño”, contenido en la Convención Internacional de Derechos del Niño, en el razonamiento jurídico justificatorio. Dos  ideas fundamentales son defendidas
Ricardo Garrido Álvarez
doaj   +1 more source

La aplicación de los derechos humanos en el interés superior del niño

open access: yesIustitia Socialis, 2020
La naturaleza tutelar  del interés superior del niño es un elemento sobre el que se construyen  derechos. El objetivo lograr una aplicación e interpretación uniforme de la directriz, a efectos de que las sentencia y resoluciones logren consolidar el ...
Pablo Fernando Almeida-Toral   +3 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

El síndrome de alienación parental en la jurisprudencia de la Corte Constitucional colombiana

open access: yesTelos: Revista de Estudios Interdisciplinarios en Ciencias Sociales
El síndrome de alienación parental ha sido considerado como un fenómeno que desconfigura las relaciones familiares, atentando contra el interés superior de los niños, niñas y adolescentes, sin embargo, jurídicamente se desconocen los efectos de su ...
Sergio Luis Mondragón Duarte   +2 more
doaj   +1 more source

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