Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen +10 more
wiley +1 more source
A Multiplex TaqMan qPCR Assay for Rapid Detection of <i>Streptococcus suis</i> Serotypes 1, 2, 7, and 9 with Cross-Reactivity to Serotypes 14 and 1/2. [PDF]
Huang J +8 more
europepmc +1 more source
RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites
At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo +10 more
wiley +1 more source
OATrack: A Quality-Gated Progressive Association Framework with a YOLO Detection Cache for UAV Small-Object Multi-Object Tracking. [PDF]
Qi L, Wang L, Jiang S.
europepmc +1 more source
Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer +17 more
wiley +1 more source
Integration of an iterative factor into a validated HPTLC method for quantification of koumine in the toxic plant <i>Gelsemium elegans</i> Benth. [PDF]
Ng CH +8 more
europepmc +1 more source
Inspired by antifreeze glycoproteins (AFGPs), we synthesized a type of oligomeric cellulose (OC‐8) to inhibit ice formation and enlarge the inter‐ice water channel for transportation. Typical confocal fluorescence experiments display the expansion of the ice‐water interface for zinc‐ion transport.
Zeyu Zhu +12 more
wiley +1 more source
Towards causal validation and clinical translation of the PAK2-fibroblast axis in idiopathic pulmonary fibrosis. [PDF]
Sun M, Zang D, Chen J.
europepmc +1 more source
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho +13 more
wiley +1 more source
Differential contributions of working memory and inhibitory control to prospective memory detection and retrieval. [PDF]
Alnajashi SA.
europepmc +1 more source

