Results 31 to 40 of about 249,354 (247)

Enhancing Log-Likelihood Ratios with Mutual Information on Three-Reader One-Track Detection in Staggered BPMR Systems

open access: yesApplied Sciences
Because so much information is currently being shared online, there has been a sharp rise in the need for data storage devices over the past ten years. The main storage option is the hard disk drive (HDD), which is less expensive than some other types of
Natthakan Rueangnetr   +4 more
doaj   +1 more source

Production of $e^+e^-$ Pairs Accompanied by Nuclear Dissociation in Ultra-Peripheral Heavy Ion Collision [PDF]

open access: yes, 2004
We present the first data on $e^+e^-$ pair production accompanied by nuclear breakup in ultra-peripheral gold-gold collisions at a center of mass energy of 200 GeV per nucleon pair.
A. A. Derevschikov   +371 more
core   +5 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Determining The Geometrical Parameters Of Exploited Rail Track Using Approximating Spline Functions

open access: yesArchives of Civil Engineering, 2014
The process of railway track adjustment is a task which includes bringing, in geometrical terms, the actual track axis to the position ensuring safe and efficient traffic of rail vehicles.
Lenda G.
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Two-Dimensional 15/24 Non-Isolated Patterned Modulation Codes With Minimum Hamming Distance 3 in Bit-Patterned Media Recording

open access: yesIEEE Access
Reducing the distance between magnetic islands is essential for increasing the areal density in bit-patterned media recording (BPMR). Consequently, significant two-dimensional (2D) interference emerges, encompassing inter-symbol interference (ISI) and ...
Thien An Nguyen, Jaejin Lee
doaj   +1 more source

Soft-information flipping scheme based on a priori LLRs summation for ultra-high density magnetic recording

open access: yesAIP Advances, 2020
Inter-track interference (ITI) is the main problem in high areal density (AD) of magnetic recording systems such as bit-patterned magnetic recording (BPMR) technology thus the ITI avoidance scheme is the way to improve the performance of the recording ...
W. Busyatras, C. Warisarn
doaj   +1 more source

Throughput and Robustness Guaranteed Beam Tracking for mmWave Wireless Networks

open access: yes, 2017
With the increasing demand of ultra-high-speed wireless communications and the existing low frequency band (e.g., sub-6GHz) becomes more and more crowded, millimeter-wave (mmWave) with large spectra available is considered as the most promising frequency
Fang, Xuming, Long, Yan, Zhou, Pei
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

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