Results 51 to 60 of about 6,226 (224)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Central Institute of Psychiatry: A fictional journey to past in a time machine

open access: yesIndian Journal of Psychiatry, 2018
A fictional journey was planned and carried out in a time machine, to know and understand the glorious past of Central Institute of Psychiatry (CIP), Ranchi. As Dr. Anand, the protagonist, went through different periods in the history of CIP, he narrated
Tapas Kumar Aich   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

"Konfettaskar" och "typografiska läckerbitar" eller funktionalistisk formgivning? Om Eva Billow som bilderbokskonstnär och grafiker

open access: yesBarnboken: Tidskrift för Barnlitteraturforskning, 2012
Eva Billow as picture book artist and graphic designer. The 1940’s and 50’s was a dynamic period for the Nordic picture book. There is a general aspiration to explore picture book aesthetics, a need to find imagery and expressions capturing a new era. In
Elina Druker
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

A Performance-Theory Revisit of the Conflict Scene at the Ventershoek (2927CA1) Rock Art Site

open access: yesArts
Late contact-era depictions of inter-group conflict in southern African rock art include references to the image-makers and their opponents, who must also have been able to view the images.
David M. Witelson
doaj   +1 more source

Telling the truth: Don DeLillo in an age of amnesia and redress

open access: yesIlha do Desterro, 2010
The December 2006 Iran Holocaust denial Conference and the international excoriation of it reveal a paradox of two cultural strands that are emblematic of the legacy of the twentieth century: official denial and historical amnesia on the one hand; and ...
Marni Gauthier
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

A General Legislative Analysis of "Torture" as a Human Rights Violation in Zimbabwe

open access: yesPotchefstroom Electronic Law Journal, 2017
Several challenges involving torture-related human rights violations have been reported in Zimbabwe from the late 1970s to date. Notably, these torture-related human rights violations were problematic during the liberation war era in Zimbabwe ...
Howard Chitimira, Pontsho Mokone
doaj   +1 more source

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