Results 121 to 130 of about 102,804 (316)

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Resolving Black Hole Family Issues among the Massive Ancestors of Very High-spin Gravitational-wave Events like GW231123

The Astrophysical Journal Letters
The latest detection of GW231123, a black hole (BH) merger with exceptionally large component masses and high spins, has been suggested as a smoking gun for hierarchical formation. In this scenario, a first generation of BHs form from collapsing stars in
Jakob Stegmann, Aleksandra Olejak, Selma E. de Mink   +2 more
doaj   +1 more source

High mass X-ray binaries in the NIRorbital solutions of two highly obscured systems [PDF]

, 2010
The maximum mass of a neutron star (NS) is poorly defined. Theoretical attempts to define this mass have thus far been unsuccessful. Observational results currently provide the only means of narrowing this mass range down.
Clark, J. S., Mason, A. B., Negueruela, I., Norton, A. J., Roche, P.   +4 more
core   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Runaway OB Stars in the Small Magellanic Cloud. III. Updated Kinematics and Insights into Dynamical versus Supernova Ejections

The Astrophysical Journal
We use the kinematics of field OB stars to estimate the frequencies of runaway stars generated by the dynamical ejection scenario (DES), the binary supernova scenario (BSS), and the combined two-step mechanism.
Grant D. Phillips, M. S. Oey, Maria Cuevas, Norberto Castro, Rishi Kothari   +4 more
doaj   +1 more source

Interacting Binary White Dwarf Stars [PDF]

, 1992
J.‐E. Solheim
openalex   +1 more source

Copper‐based Materials for Photo and Electrocatalytic Process: Advancing Renewable Energy and Environmental Applications

Advanced Functional Materials, EarlyView.
Cu‐based catalysts as a cornerstone in advancing sustainable energy technologies are fully reviewed in this manuscript, highlighting their potential in photo‐ and electrocatalysis. It includes metallic copper, copper oxides, copper sulfides, copper halide perovskites, copper‐based metal–organic frameworks (MOFs), and covalent organic frameworks (COFs),
Jéssica C. de Almeida, Yanjie Wang, Thais A. Rodrigues, Paulo H. H. Nunes, Vagner R. de Mendonça, Paulo H. E. Falsetti, Leticia V. Savazi, Tao He, Alexandra V. Bardakova, Aida V. Rudakova, Jie Tian, Alexei V. Emeline, Osmando F. Lopes, Antonio Otavio T. Patrocínio, Jia Hong Pan, Caue Ribeiro, Detlef W. Bahnemann   +16 more
wiley   +1 more source

The HST Nondetection of SN Ia 2011fe 11.5 yr after Explosion Further Restricts Single-degenerate Progenitor Systems

The Astrophysical Journal
We present deep Hubble Space Telescope imaging of the nearby Type Ia supernova (SN Ia) 2011fe obtained 11.5 yr after explosion. No emission is detected at the SN location to a 1 σ (3 σ ) limit of F555W > 30.2 (29.0) mag, or equivalently M _V > 1.2 (−0.1)
M. A. Tucker, B. J. Shappee
doaj   +1 more source

Be Stars as Interacting Binaries [PDF]

, 1982
Geraldine J. Peters
openalex   +1 more source

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

Advanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er, Martha Patricia Pérez González, Beatriz Gil Garrido, Jasmine Ho, Hae‐Won Kim, Jonathan Campbell Knowles, Jia Hua, Ferdinand Lali, Prasad Sawadkar   +8 more
wiley   +1 more source