Results 161 to 170 of about 5,221,406 (297)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Unwiring jasmonic acid defense signaling: Molecular regulation and ecological costs
, 2015 In natural environments, plants have to deal with a wide diversity of attackers, resulting in major crop losses in agricultural settings. Plant can activate defense responses against these attackers, however, there are fitness penalties like reduced ...
Vos, I.A. +2 more
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Cyber operations as a facet of international competition pose a direct challenge to alliances. Designed to respond to conventional military attacks, alliances like the North Atlantic Treaty Organization must now determine how their defensive commitments ...
Interactions, International
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
, 1996 34 pages. Appeared in in Proceedings of the 1996 CLiCS Summer School, Isaac Newton Institute, P. Dybjer and A. Pitts, eds.
openaire +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Here are the replication files for Knapp (2024), "Speaking of civilians: Automated text analysis of the United Nations’ framing of complex humanitarian emergencies" International ...
Interactions, International
core +1 more source
Biotic interactions biogeography: A framework for understanding how species interactions shape biodiversity patterns across scales. [PDF]
PLoS BiolGaliana N, Araújo MB.
europepmc +1 more source