Results 111 to 120 of about 1,657,032 (289)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

PENGARUH PENGGUNAAN MEDIA PEMBELAJARAN INTERAKTIF DALAM MENINGKATKAN MINAT BELAJAR SISWA

open access: yesEdusaintek
This research aims to determine the effect of using interactive learning media in increasing students' interest in learning at SDN Giriwinaya. The purpose of the study is to describe the effect of using interactive learning media in increasing students'
Ricky Yoseptry   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Assessing Emission Allocation in Europe: An Interactive Simulation Approach [PDF]

open access: yes
Implementation of an EU-wide emissions trading system by means of National Allocation Plans is at the core of European environmental policy agenda. Member States are faced with the problem of allocating their national emission budgets under the EU Burden
Böhringer, Christoph   +4 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

service-oriented approach for interactive computing systems

open access: yesPublicaciones en Ciencias y Tecnología, 2011
The introduction of new technologies leads to a more and more complex interactive systems design. In order to describe the future interactive system, the human computer interaction domain uses specific models, design processes and tools in order to ...

doaj  

Home - About - Disclaimer - Privacy