Results 231 to 240 of about 370,157 (266)

Web-based collaborative model development in interdisciplinary consortia: Design principles and practical guidance. [PDF]

PLoS Biol
van Aalst M, Lahlou A, Hassan T, Gaultier W, Colliaux D, Matuszyńska A.   +5 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Building an interactive dashboard to visualize institutional open access publishing trends. [PDF]

J Med Libr Assoc
Gorman EF, Shelawala N, Yarnell A.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Towards the ecological automated measurement of joint attention: Development of an interactive eye-tracking battery for joint attention in children with and without autism. [PDF]

Behav Res Methods
Yoon CD, Meadan H, Shic F.
europepmc   +1 more source

The effect of a modified Peyton's four-step teaching method on orthokeratology skills: an experimental study. [PDF]

Front Med (Lausanne)
Wang J, Zhang K, Wan Q, Zheng Y, Tao L, Ling L.   +5 more
europepmc   +1 more source

Using Sound to Simulate Tactile Cues: AI-Generated Audio and Pseudo-Haptics in Medical Simulation. [PDF]

Cureus
Abdo S, Kapralos B, Collins KC, Dubrowski A.   +3 more
europepmc   +1 more source