Results 41 to 50 of about 247,414 (295)

A tool for subjective and interactive visual data exploration [PDF]

, 2016
We present SIDE, a tool for Subjective and Interactive Visual Data Exploration, which lets users explore high dimensional data via subjectively informative 2D data visualizations.
C Ware, D Paurat, DJ Hand, J Lijffijt, T Bie De, T Ruotsalo, V Dzyuba   +6 more
core   +2 more sources

DAPPER: a data-mining resource for protein-protein interactions [PDF]

BioData Mining, 2015
BACKGROUND: The identification of interaction networks between proteins and complexes holds the promise of offering novel insights into the molecular mechanisms that regulate many biological processes. With increasing volumes of such datasets, especially in model organisms such as Drosophila melanogaster, there exists a pressing need for specialised ...
Haider, Syed, Lipinszki, Zoltan, Przewloka, Marcin R, Ladak, Yaseen, D'Avino, Pier Paolo, Kimata, Yuu, Lio', Pietro, Glover, David M   +7 more
openaire   +5 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Integrating Text Mining into the Curation of Disease Maps

Biomolecules, 2022
An adequate visualization form is required to gain an overview and ultimately understand the complex and diverse biological mechanisms of diseases. Recently, disease maps have been introduced for this purpose.
Malte Voskamp, Liza Vinhoven, Frauke Stanke, Sylvia Hafkemeyer, Manuel Manfred Nietert   +4 more
doaj   +1 more source

Interactive visual exploration of association rules with rule-focusing methodology [PDF]

, 2007
International audienceOn account of the enormous amounts of rules that can be produced by data mining algorithms, knowledge post-processing is a difficult stage in an association rule discovery process.
Blanchard, Julien, Briand, Henri, Guillet, Fabrice   +2 more
core   +4 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Roadside Perception System Based on LiDAR and Millimeter-wave Radar Fusion in Mining Area

Kongzhi Yu Xinxi Jishu, 2022
In view of the shortcomings of the current onboard perception system in mining areas and the limitations of single sensor sensing, this paper analyzes the feasibility of using roadside perception system to provide additional sensing information for ...
JIANG Liangyu
doaj   +3 more sources

Integrated Performance and Visualization Enhancement of OLAP Using Growing Self Organizing Neural Networks

Journal of Advances in Information Technology, 2010
OLAP performance and its data visualization can be improved using different types of enhancement techniques. Previous research has taken two separate directions in OLAP performance improvement and visualization enhancement respectively. Some recent works
Muhammad Usman, Sohail Asghar, Simon Fong   +2 more
doaj   +1 more source

Data mining technology for the evaluation of learning content interaction [PDF]

, 2004
Interactivity is central for the success of learning. In e-learning and other educational multimedia environments, the evaluation of interaction and behaviour is particularly crucial.
Pahl, Claus
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source