Results 51 to 60 of about 268,171 (278)

COMPARISON OF 3D RECONSTRUCTION SERVICES AND TERRESTRIAL LASER SCANNING FOR CULTURAL HERITAGE DOCUMENTATION [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2013
Terrestrial Laser Scanning (TLS) is an established method to reconstruct the geometrical surface of given objects. Current systems allow for fast and efficient determination of 3D models with high accuracy and richness in detail.
S. Rasztovits, P. Dorninger
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Design of solar systems for buildings and use of BIM tools: Overview of relevant geometric aspects [PDF]

FME Transactions, 2019
The paper systematizes geometric aspects relevant for understanding design of solar systems. The systematization is based on a review of literature dedicated to various kinds of engineers, including architects, involved in a multidisciplinary process of ...
Devetaković Mirjana S., Đorđević Đorđe D., Đukanović Gordana D., Krstić-Furundžić Aleksandra D., Sudimac Budimir S., Scognamiglio Alessandra   +5 more
doaj  

Automatic Deduction in Dynamic Geometry using Sage

, 2012
We present a symbolic tool that provides robust algebraic methods to handle automatic deduction tasks for a dynamic geometry construction. The main prototype has been developed as two different worksheets for the open source computer algebra system Sage,
Abánades, Miguel A., Botana, Francisco
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Enhancing Students' van Hiele Geometric Thinking Levels Through the Integration of Geometer's Sketchpad (GSP) in Geometry Learning

Qubahan Academic Journal
Van Hiele’s theory of geometric thinking describes a hierarchical progression through distinct levels, from basic visualization to advanced deductive reasoning.
Sugi Hartono, Rezky Ramadhona, Sri Irawati, Diena Frentika, Heru Tri Novi Rizki   +4 more
doaj   +1 more source

A system for computerised retinal haemorrhage analysis

BMC Research Notes, 2009
Background Our aim was to develop an objective computerised system for measuring different types of retinal haemorrhages in differing digital images, for use as a research tool.
Richardson Matthew, Chua Paul, Aslam Tariq, Patel Praveen, Musadiq Mohammed   +4 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Effects of virtual acoustics on dynamic auditory distance perception [PDF]

, 2017
Sound propagation encompasses various acoustic phenomena including reverberation. Current virtual acoustic methods, ranging from parametric filters to physically-accurate solvers, can simulate reverberation with varying degrees of fidelity.
Atul Rungta, Dinesh Manocha, Ming Lin, Nicholas Rewkowski, Roberta Klatzky, Schroeder M. R., Speigle J. M., Valimaki V., Zahorik P.   +8 more
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source