Results 41 to 50 of about 1,472,267 (235)
Advanced Science, EarlyView.Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu +13 more
wiley +1 more source
Telling interactive stories: A practice-based investigation into new media interactive storytelling [PDF]
, 2009 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Telling Interactive Stories is a practice-based thesis, which theoretically and practically probes the field of digital fictional interactive storytelling ...
Atkinson, Sarah
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Advanced Science, EarlyView.ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun +10 more
wiley +1 more source
Pratiques télévisuelles et pratiques en ligne
Communication, 2016 The author examines the complex phenomenon of the dialectical relationship between imagined and actual internet audiences, first by examining the way professional practices construct the experience of bloggers appearing live via webcam on CULT, the ...
Céline Ferjoux
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Advanced Science, EarlyView.An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng +9 more
wiley +1 more source
Nowy model konsumpcji treści telewizyjnych – użytkownik zdobywa przewagę nad oferentem telewizji
Studia i Materiały, 2012 The new media technologies offered more possibilities to the user and equipped him with the instruments to takeover the control or establish the dialogue with the broadcaster. The viewer becomes the editor of his own TV program.
Monika Mizielińska-Chmielewska
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PARADIGMA BARU MENGEMAS DAKWAH MELALUI MEDIA TELEVISI DI ERA GLOBALISASI
Komunika, 2015 In this global era, da’wah through television has an important role in human development, especially akhlaq, moral, and character development. At present, television should deliver da’wah programs with a new paradigm adopting 5 basic elements: 1) as the ...
Fatmawati Fatmawati
doaj +3 more sources
Advanced Science, EarlyView.GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han +16 more
wiley +1 more source
Gap‐Free Information Transfer in 4D‐STEM via Fusion of Complementary Scattering Channels
Advanced Science, EarlyView.Fused Full‐Field STEM (FF‐STEM) is introduced as a 4D‐STEM imaging modality that combines direct ptychography with tilt‐corrected dark‐field reconstruction in a single acquisition. Fourier‐space fusion using Wiener‐type spectral weighting closes the low‐frequency contrast gap inherent to bright‐field methods, delivering gap‐free, dose‐efficient, near ...
Shengbo You +15 more
wiley +1 more source
Хабаршы Журналистика сериясы, 2020 Discourse got to all types of institutional and everyday communica tion. However television discourse remains an insufficiently known area. Research actuality consists in insufficient studied of genre specific.
Ормаханова Е.Н.
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