Results 51 to 60 of about 4,361 (158)

Comprehensive Assessment of the KDM2B‐Associated Neurodevelopmental Disorder and the 12q24.31 Microdeletion Syndrome

Clinical Genetics, EarlyView.
We set out to characterize genotype–phenotype correlations in the recently delineated KDM2B‐associated neurodevelopmental disorder. We observe a highly penetrant CxxC domain‐related phenotype with distinct facial features supported by GestaltMatcher. In contrast, our findings point to variable expressivity and incomplete penetrance of loss‐of‐function ...
Amber S. E. van Oirsouw, Tzung‐Chien Hsieh, Martijn Koetsier, Abdulrazak Alali, Fatimah Albuainain, Elena Bacchelli, Tahsin Stefan Barakat, Yline Capri, Sandra Chantot‐Bastaraud, Valeria Capra, Deanna Alexis Carere, Emma Clement, Nour Elkhateeb, Madeleine Franchi, Jing‐Mei Li, Nicole Matthews, Vanda McNiven, Sarju G. Mehta, Masayuki Nakamura, Chanika Phornphutkul, Nicole Revencu, Marcello Scala, Natalie Shallow, Jennifer Stefanich, Marta Viggiano, Paola Visconti, Susan Walker, Federico Zara, Mariëlle Alders, Bobby P. C. Koeleman, Renske Oegema   +30 more
wiley   +1 more source

Navigating the Zero Fluoroscopy Frontier: Current Tools, Evidence and Future Directions in Electrophysiology Procedures

Pacing and Clinical Electrophysiology, EarlyView.
Graphical Abstract ABSTRACT Fluoroscopy has traditionally been the mainstay imaging technique for guidance during electrophysiology (EP) ablation procedures. The numerous disadvantages associated with radiation exposure for both operators and patients have created the need for zero‐fluoroscopy (ZF) approaches. Today, electrophysiologists have access to
Dimitrios Kotzadamis, Georgios Giannopoulos, Vaios Schismenos, Alexandros Evangeliou, Prokopios Mamolis, Antonios Antoniadis, Vassilios Vassilikos   +6 more
wiley   +1 more source

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

Atrial Flutter as a Late Presentation of Scimitar Vein in an Adult With Prior ASD Repair

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Adult patients with unexplained atrial arrhythmias and right heart dilation should prompt consideration of congenital anomalies such as scimitar vein, even decades after atrial septal defect repair. Early recognition using multi‐modality imaging may prevent delayed diagnosis and progressive cardiopulmonary complications.
Fereshte Rastegarnasab, Zahra Teimouri‐Jervekani, Keyvan Khojaste, Azam Soleimani   +3 more
wiley   +1 more source

Cerebral Embolism Beyond Atrial Fibrillation: Interatrial Block

, 2020
This paper is devoted to conditions that imply a risk for cerebral embolism beyond atrial fibrillation (AF). We focus on advanced interatrial block (IAB) and its relationship with stroke in elderly patients with no documented arrhythmias. Advanced IAB is
Martínez-Sellés, Manuel, Ayesta, Ana, Martínez-Sellés, Helena   +2 more
core   +1 more source

Persistent Arrhythmogenic Effects of COVID‐19: A Comprehensive Analysis of Device Implantation and Antiarrhythmic Interventions in Japan

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
COVID‐19 was associated with a sustained increase in device implantation and arrhythmia‐related interventions over 2 years. In a nationwide propensity score‐matched cohort, risks of pacemaker, ICD, CRT implantation, ablation procedures, and antiarrhythmic medication initiation remained higher after COVID‐19, supporting long‐term cardiovascular ...
Daisuke Miyamori, Shuhei Yoshida, Masanori Ito   +2 more
wiley   +1 more source

Horizontal Heart Orientation as a Mechanistic Contributor to Platypnea–Orthodeoxia Syndrome in Patent Foramen Ovale

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Altered cardiac orientation in the presence of a patent foramen ovale (PFO) can contribute to platypnea–orthodeoxia syndrome (POS) and unexplained hypoxemia. In such cases, consideration of PFO closure may lead to significant clinical improvement.
Bijeta Keisham, Sanchit Duhan, Uday B. Kanakadandi, Osama Alsara, Naveed A. Adoni, Sanjay S. Mehta, Andrea Brasch, Haseeb Basha, Vishesh Paul   +8 more
wiley   +1 more source

Late‐Onset Third Degree Atrioventricular Block in Adult With Surgically Corrected Ebstein Anomaly: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Late‐onset third‐degree atrioventricular (AV) block is a rare life‐threatening complication that may develop years after surgical correction of Ebstein anomaly. Effective management depends on routine cardiac monitoring and timely intervention with an epicardial permanent pacemaker.
Bishal Kumar Yadav, Bishal Sigdel, Bishal Mandal, Abhishek Mahato, Bishal Basnet, Samir Yadav, Anil Bhattarai   +6 more
wiley   +1 more source

Interatrial blocks prevalence and risk factors for human immunodeficiency virus-infected persons

, 2019
[eng] Background Interatrial blocks are considered a new important risk factor for atrial fibrillation and cerebrovascular events. Their prevalence and clinical implications have been reported in general population and several subgroups of patients but ...
Sampériz, Gloria, Yañez, Aina, Riera, Melchor, Campins, Antoni, Romaguera, Dora, Fanjul, Francisco, Asensio, Javier, Fiol, Miquel   +7 more
core   +2 more sources

Advancements and Applications of Focused Assessed Transthoracic Echocardiography: A Narrative Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Focused Assessed Transthoracic Echocardiography (FATE), developed by Dr. Erik Sloth in 1989, has become a key ultrasound technique for rapid bedside assessment of cardiac function. Its non‐invasive nature, real‐time imaging, and portability make it ideal for facilitating swift clinical decisions across various specialties ...
Habib Olatunji Alagbo, Oluwaremilekun Zeth Tolu‐Akinnawo, Isaac Adewumi Babawale, Charles Oluwarotimi Poluyi, Selimat Ibrahim, Jonas Lotanna Ibekwe, Dania Jaamour, Toluwalase Awoyemi   +7 more
wiley   +1 more source