Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater +13 more
wiley +1 more source
Interactions of Cyclic Peptides Ribifolin and Gramicidin S with Montmorillonite Surface by Molecular Modeling. [PDF]
Sousa LHN +3 more
europepmc +1 more source
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang +12 more
wiley +1 more source
Symmetry-Guided Functional Pathways of Intercalation-Free Rhombohedral (<i>R3</i>) Hafnia Derived from the Fluorite Phase for Low-Coercive Ferroelectric Memory. [PDF]
Januar M +5 more
europepmc +1 more source
Disorder‐Induced Extremely Low Thermal Conductivity of Graphite Fluoride
This article investigates the effect of fluorination on the thermal conductivity of graphite fluoride, demonstrating the relationship between structural modification and thermal conductivity in an extreme case. The record‐low through‐plane thermal conductivity measured in exfoliated graphite fluoride flakes was found to correlate with the wide ...
Wonsik Lee +10 more
wiley +1 more source
Molecular Insights of 7‑Azaindole Drugs and Their Intercalation in the Confined Space of Montmorillonite. [PDF]
Borrego-Sánchez A +3 more
europepmc +1 more source
Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh +11 more
wiley +1 more source
Interlayer co-chemistry of a homologous ion stabilizer and microenvironmental molecular regulator for high-performance zinc-ion storage. [PDF]
Chen K +10 more
europepmc +1 more source
Lithiophilic Current Collector Without Interfacial Penalty in Zero‐Excess Lithium Metal Batteries
Bilayer lithiophilic coatings are introduced to overcome the structural fragility of conventional single‐layer current collectors in zero‐excess Li‐metal batteries (ZE‐LMBs). By integrating density functional theory with electrochemical analyses, the Ag‐outer/Pt‐inner configuration enables uniform Li deposition, robust SEI formation, and persistent ...
Jiyeon Seo +8 more
wiley +1 more source

