Results 111 to 120 of about 45,259 (294)

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

The Educational Environment According to the Qur'an and Hadith: Perspectives and Implications

Al Muhafidz
The educational environment in Islam plays a strategic role in shaping students' character. This study aims to explore the concept of the academic environment from the perspective of the Qur'an and Hadith and analyze its implications for the formation ...
Inayah Inayah, Moh Ali, Ade Hidayat, Titin Yuniartin   +3 more
doaj   +1 more source

Popularity enhances the interdependent network reciprocity

New Journal of Physics, 2018
Interdependent networks (IN) are collections of non-trivially interrelated graphs that are not physically connected, and provide a more realistic representation of real-world networked systems as compared to traditional isolated networks.
Chen Liu, Chen Shen, Yini Geng, Shudong Li, Chengyi Xia, Zhihong Tian, Lei Shi, Ruiwu Wang, Stefano Boccaletti, Zhen Wang   +9 more
doaj   +1 more source

Independent-interdependent Self-construal's and Values’ Appreciation in Competitive and Cooperative Conditions

, 2012
Cooperative and competitive strategies are applied in a variety of instructional activities from higher education. Cooperation and competition require different sets of values that may be acquired of students in their learning experiences and academic ...
Cristina-Corina, Bentea
core   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

Molecular Glue cc‐885 Inhibits VHL‐Deficient Clear Cell Renal Cell Carcinoma via ETS1 Degradation

Advanced Science, EarlyView.
VHL‐deficient kidney cancer lacks effective treatments. This study reveals that the molecular glue degrader cc‐885 hijacks the cellular recycling system to selectively destroy the oncogenic protein ETS1, effectively killing VHL‐mutant tumors. Combining CC‐885 with the approved drug belzutifan achieves powerful synergy, offering a promising new ...
Taowei Yang, Qihao Li, Kun Ye, Kezhi Liu, Mi Zhou, Minyu Chen, Lican Liao, Kangbo Huang, Zhu Wang, Qiong Deng, Jieyan Wang, Meiyu Jin, Xu Chen, Hui Liang, Jiaxing Zhang, Junhang Luo   +15 more
wiley   +1 more source

Tunable Negative Thermal Expansion in Fe/Cr‐Substituted Nd2Co17 Compounds via Magnetoelastic Coupling

Advanced Science, EarlyView.
This study achieves anisotropic thermal expansion tuning in Nd2(Co1‐xFex)17‐yCry compounds via a magnetoelastic strategy. Variable‐temperature synchrotron X‐ray diffraction reveals that increased Fe content induces switchable lattice responses. Compositional control reduces the volume expansion coefficient αV by 20% (x═0.7) and modulates TC (442–625 K),
Jiayuan Li, Chenfei Qv, Haoran Tu, Qinfen Gu, Wayne D. Hutchison, Stewart J. Campbell, Zhenxiang Cheng, Wenquan Wang, Jianli Wang   +8 more
wiley   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Resource Allocation of Cooperative Alternatives Using the Analytic Hierarchy Process and Analytic Network Process with Shapley Values

Algorithms
Cooperative alternatives need complex multi-criteria decision-making (MCDM) consideration, especially in resource allocation, where the alternatives exhibit interdependent relationships.
Jih-Jeng Huang, Chin-Yi Chen
doaj   +1 more source

A Generalized Vickrey Auction [PDF]

In auction environments where bidders have pure private values, the Vickrey auction (Vickrey, 1961) provides a simple mechanism for efficiently allocating homogeneous goods.
Lawrence Ausubel
core