Results 191 to 200 of about 234,151 (268)

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, EarlyView.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai, Keyu Wang, Jiali Fang, Shaorui Jia, Yansong Shi, Wanfeng Gao, Xinpeng Liu, Jiaqiang Li, Zenghui Cui, Yazhi Qian, Xiaosu Chen, Dan Ding, Xuetao Cao   +12 more
wiley   +1 more source

Interdisciplinary Approach in Pediatric Patients With Recessive Dystrophic Epidermolysis Bullosa: Experience From the Dermatology Service and the Palliative Care and Complex Chronic Patient Team at Sant Joan de Déu Hospital (Barcelona, Spain). [PDF]

J Eval Clin Pract
Martínez-Ripoll JM, García-Domingo M, De la Fuente Robles YM.   +2 more
europepmc   +1 more source

Graphene (0002)/Diamond (111) Heterojunction with High Piezoresistive Response

Advanced Science, EarlyView.
Graphene/diamond heterostructures show promise as silicon alternatives for semiconductors, but high‐quality integration is challenging. Thermal electron irradiation enables covalent bonding; lonsdaleite acts as an intermediate. The heterostructure exhibits a high piezoresistive response (gauge factor −1149) associated with electron‐rich layers and ...
Xueyu Zhang, Kun Guo, Zhigang Gai, Tianxiao Guo, Yuan Gao, Jiancai Leng, Mei Zhang, Tonggang Jiu, Yibao Wang, Shousheng Liu, Xin Jiang   +10 more
wiley   +1 more source

Adverse Pregnancy Outcomes in Sjogren's Disease Compared to Controls: An Interdisciplinary Approach with Maternal-Fetal Medicine. [PDF]

AJP Rep
Tesoriero L, Kidd J, Piccione J, Izmirly P, Akerman M, Carsons S, Rekawek P, Nusbaum J.   +7 more
europepmc   +1 more source

2D Inorganic Electrides: Interstitial Electrons as Key Drivers of Multifunctional Properties and Applications

Advanced Science, EarlyView.
Eight AB‐type 2D inorganic electrides with negatively charged transition metals are theoretically designed. Their monolayers exhibit intrinsic magnetic ordering, rich topological phases, and ultralow work functions. Supported metal Ru on these 2D inorganic electrides effectively alleviates hydrogen poisoning and enables efficient ammonia synthesis ...
Qianwen Zhang, Xia Cheng, Zhenzhou Guo, Weiyao Jia, Ying Yang, Zhenxiang Cheng, Weizhen Meng   +6 more
wiley   +1 more source

Integrating geographic information systems into veterinary education within the one health framework: an interdisciplinary approach. [PDF]

Front Vet Sci
Contreras A, Cuevas V, Rivera-Gomis J, Sánchez A, Acevedo P, Vicente J.   +5 more
europepmc   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

Advanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio, Wei Xuan Wilson Loo, Yan Shan Loo, Wen Xin Tan, Hui Xuan Lim, Huitao Liu, Chen Seng Ng   +6 more
wiley   +1 more source

Complication-Free Intra-operative Mismatched Blood Transfusion Under General Anesthesia With an Interdisciplinary Approach: A Case Report. [PDF]

Cureus
Jastanyah A, Niyaz RI, Bokhari A, Zia M.
europepmc   +1 more source

Boosting Ferroelectricity: 2D and Polymer Ferroelectric Hybrids Enabling Ambipolar Nonvolatile MoS2 Memory Transistor

Advanced Science, EarlyView.
Two‐dimensional CuInP2S6 nanosheets are incorporated into a P(VDF‐TrFE) matrix to induce polarization‐cooperative ferroelectric coupling. The resulting P(VDF‐TrFE)/CuInP2S6 hybrid film exhibits reinforced ferroelectric ordering and reduced coercive electric fields compared with pristine P(VDF‐TrFE).
Yeonsu Jeong, Honglei Wang, Pietro Tordi, Ying Chieh Hu, Adrián Tamayo, Bing Wu, Hyun Soo Ahn, Zdenek Sofer, Jong Hoon Jung, Massimo Bonini, Paolo Samorì   +10 more
wiley   +1 more source

Interdisciplinary approach in the management of visual loss in giant cell arteritis. [PDF]

Saudi J Ophthalmol
De Simone L, Marvisi C, Ricordi C, Gozzi F, Bolletta E, Gentile P, Muratore F, Cimino L, Salvarani C.   +8 more
europepmc   +1 more source